“…Aparecen aglomeraciones de células en la periferia del injerto sobre la 6ª semana con grandes zonas acelulares en el centro del injerto. Estas regiones hipercelulares son MSC [218] y fibroblastos activados [140] que secretan factores de crecimiento para mantener la remodelación del injerto. El pico de producción de estos factores es entre la 3ª y 6ª semana y cesa completamente a partir de la 12ª semana.…”
“…Aparecen aglomeraciones de células en la periferia del injerto sobre la 6ª semana con grandes zonas acelulares en el centro del injerto. Estas regiones hipercelulares son MSC [218] y fibroblastos activados [140] que secretan factores de crecimiento para mantener la remodelación del injerto. El pico de producción de estos factores es entre la 3ª y 6ª semana y cesa completamente a partir de la 12ª semana.…”
“…Dies wurde von mehreren Autoren bestä-tigt [5,8,9,22,26]. Seit dem biomechanischen Nachweis, dass die Zwei-Bündel-Rekonstruktion (VierKanal-Technik) sowohl hinsichtlich der anterioren Translation als auch der anterioren Translation in Innenrotation der Ein-Bündel-Technik überlegen ist [31], wird die Zwei-Bündel-Technik zunehmend empfohlen [1,10,20,23,30,32]. Yagi et al konnten zudem in objektiven klinischen Untersuchungen einen Vorteil der Zwei-Bündel-Rekonstruktion (Vier-KanalTechnik) bezüglich der Rotationsstabilität nachweisen [29].…”
Section: Vorbemerkungenunclassified
“…Other authors have also described the bundles [5,8,9,22,26]. Some biomechanical evidence shows that double-bundle reconstruction with two double-looped grafts is superior to one-bundle technique with regard to both anterior translation and anterior translation in internal rotation [31], thus the two-bundle technique is being increasingly recommended [1,10,20,23,30,32]. In a clinical study, Yagi et al were also able to show improved rotatory stability with the double-bundle technique [29].…”
From May 2004 to June 2005, anatomic double-bundle reconstruction was performed in 19 patients (13 male, six female, average age 31 years [18-48 years]) with isolated anterior cruciate ligament rupture without concomitant lesions. Clinical follow-up examination on average at 21.3 months (16-30 months) postoperatively. The Lysholm Score improved from an average of 65.2 to 94.5 points (75-100 points). The IKDC (International Knee Documentation Committee) Score yielded nine very good and ten good results in the relevant subgroups of motion, effusion and ligament stability. Measurement of anteroposterior translation with the KT-1000 instrument at 134 N showed increased translation of 1.8 mm (-2 to 5 mm) compared to the contralateral knee.
“…The goal of ACL reconstruction is not only to obtain the knee stability without loss of motion, but also to restore the same kinematics as the native knee. Therefore, more anatomical reconstructions in which tendon grafts were placed at original attachment sites of each fiber bundle to mimic the native anatomy as closely as possible, were developed (Odensten and Gillquist, 1985;Muneta et al, 1999;Shino et al, 2005;Zantop et al, 2006;Otsubo et al, 2007;Siebold et al, 2008). Actually, the multiple bundle ACL reconstruction such as double bundle reconstruction has been increasingly popular in the clinical settings (Muneta et al, 1999;Otsubo et al, 2007).…”
Section: Introductionmentioning
confidence: 99%
“…Actually, the multiple bundle ACL reconstruction such as double bundle reconstruction has been increasingly popular in the clinical settings (Muneta et al, 1999;Otsubo et al, 2007). In 2005, Shino et al (2005 developed the anatomic triple-bundle method to reconstruct the three bundles by dividing the AM bundle in conventional double-bundle reconstruction into medial and lateral bundles. In addition, favorable short-term clinical outcomes of this method were reported (Mae et al, 2013).…”
The anterior cruciate ligament (ACL) is divided into three fiber bundles (AM-M: anteromedial-medial, AM-L: anteromedial-lateral, PL: posterolateral). We attempted to depict the three bundles of the human ACL on MRI images and to obtain 3-dimensional visualization of them. Twenty-four knees of healthy volunteers (14 males, 10 females) were scanned by 3T-MRI using the fat suppression 3D coherent oscillatory state acquisition for the manipulation of imaging contrast (FS 3D-COSMIC). The scanned images were reconstructed after the isotropic voxel data, which allows the images to be reconstructed in any plane, was acquired. We conducted statistical examination on the identification rate of the three ACL bundles by 2D planes. Segmentation and 3D visualization of the fiber bundles using volume rendering were performed. The triple-bundle ACL was best depicted in the oblique axial plane. While the AM-M and AM-L bundles were clearly depicted in all cases, the PL bundle was not clearly visualized in two knees (8%). Therefore, the three ACL bundles were depicted in 22 knees (92%). The results of 3D visualization of the fiber arrangement agreed well with macroscopic findings of previous anatomical studies. 3T-MRI and the isotropic voxel data from FS 3D-COSMIC made it possible to demonstrate the identifiable depiction of three ACL bundles in nearly all cases. 3D visualization of the bundles could be a useful tool to understand the ACL fiber arrangement. Clin.
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