“…Further regarding metastatic diseases, from our literature revision emerged only retrospective data of 779 patients [ 10 , 11 , 12 , 22 , 23 , 24 , 29 , 30 , 31 , 32 , 33 , 51 , 52 , 53 ], treated with a multimodality approach ( Table 1 ) and with a median overall survival that ranges from 3 to 28 months.…”