Anaplastic Carcinoma Arising in Ectopic Pancreas Located in the Distal Esophagus

Roshe, Joseph; Buono, E. Del; Domenico, Don R.; Colturi, T. J.

doi:10.1097/00004836-199604000-00022

Cited by 32 publications

(27 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Pancreatic heterotopia has been found most frequently in the upper gastrointestinal tract, and 70 to 87% of cases are in the stomach, duodenum, or jejunum. Other reported locations also have included the lung, mediastinum, esophagus, gallbladder, bile ducts, splenic hilum, colon, mediastinum, omentum, retroperitoneum, umbilicus, fallopian tubes, mesocolon, and lymph nodes (7)(8)(9)17). Therefore, an ectopic pancreas may be found in numerous organs (18).…”

Section: Discussionmentioning

confidence: 99%

“…We speculate that this anaplastic carcinoma may have originated in the ectopic pancreas located between the stomach and pancreas within the bursa omentalis. A number of carcinomas, including anaplastic type, have been reported to originate in the ectopic pancreas (8)(9)(10). If the ectopic pancreatic tissue is destroyed by tumor growth, then it would be difficult to identify the site of origin of the tumor.…”

Section: Discussionmentioning

confidence: 99%

“…Thus, an ectopic pancreas could be found in numerous organs. In addition, the malignant transformation of an ectopic pancreas is also rare (8)(9)(10).…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Anaplastic Carcinoma Possibly Arising from a Heterotopic Pancreas

Adachi¹,

Mitsuya²,

Takahashi³

et al. 2015

Intern. Med.

View full text Add to dashboard Cite

Anaplastic carcinoma is a rare pancreatic cancer, and the malignant transformation of a heterotopic pancreas is also rare. We herein report a case of an elderly woman with a mass of unknown origin in the abdominal cavity. Computed tomography identified the extent of the tumor but not the organ of origin. The abdominal tumor eventually metastasized to the liver and lung. An autopsy and immunohistochemical examination revealed an anaplastic carcinoma possibly originating in an ectopic pancreas.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Anaplastic Carcinoma Possibly Arising from a Heterotopic Pancreas

Adachi¹,

Mitsuya²,

Takahashi³

et al. 2015

Intern. Med.

View full text Add to dashboard Cite

show abstract

“…The majority of carcinomas arising within the reported examples of heterotopic pancreas have been adenocarcinomas showing ductal differentiation or have been described as anaplastic [1,4,7,[13][14][15]17,18,[23][24][25]30,32,34,36,37]. Examples of less common types of pancreatic neoplasia have been reported to occur in heterotopic pancreas, including papillary cystadenocarcinoma [29,31], acinar carcinoma [5,26], and solid and papillary neoplasm of the pancreas [20].…”

Section: Discussionmentioning

confidence: 99%

Adenocarcinoma arising in association with gastric heterotopic pancreas: A case report and review of the literature

Emerson

Layfield

Rohr

et al. 2004

Journal of Surgical Oncology

100

View full text Add to dashboard Cite

We report a case of adenocarcinoma arising in a focus of heterotopic pancreas, occurring in the stomach of a 52-year-old man. The patient presented with gastric outlet obstruction. Radiographic studies revealed thickening of the gastric wall, but endoscopy failed to reveal a mucosal abnormality. A 50% distal gastrectomy was performed, along with vagotomy. Microscopic examination revealed extensive involvement of the muscularis propria of the distal stomach by heterotopic pancreas. The ectopic pancreas had a microscopic appearance consistent with Heinrich's class III, in which the majority of the heterotopic pancreas was characterized by cystically dilated duct structures. Occasional islets were present. Intimately associated with the cystically dilated ducts was a prominent number of small infiltrating ducts lined by columnar or cuboidal cells with enlarged hyperchromatic nuclei containing prominent nucleoli. These were consistent with a well-differentiated invasive adenocarcinoma. Despite multiple sectioning, no connection between the adenocarcinoma and the overlying gastric mucosa was seen. Adenocarcinoma arising within ectopic pancreas is a rare occurrence with fewer than 30 well-documented cases reported in the world literature to our knowledge.

show abstract

“…Die Größe kann zwischen mikroskopisch klein und mehreren Zentimetern variieren [7,16]. Aberrierendes Bauchspeicheldrüsen-gewebe ist per se eine benigne Entwicklungsanomalie, in wenigen Fällen wurde aber auch schon dessen maligne Entartung diskutiert und beschrieben [11,16,18]. Der histologische Nachweis einer Fernmetastasierung gelang bis zum heutigen Zeitpunkt nicht.…”

unclassified

Heterotopes Pankreasgewebe in der Gallenblase

Neupert

Appel

Braun

et al. 2007

Chirurg

View full text Add to dashboard Cite

Ectopic pancreas is a rare entity but the second most prevalent pancreatic anomaly. Heterotopic pancreas is defined as the presence of pancreatic tissue without any anatomic or vascular continuity with the main body of the pancreas. Its aetiology is not clearly established. In 1916, Poppi published for the first time evidence of heterotopic pancreas in the gallbladder. A review of the literature up to the present showed only 28 more cases worldwide of ectopic pancreas in the gallbladder. Aberrant pancreas is incidentally discovered in 2% of autopsies and has been estimated to occur once in every 500 upper abdominal explorations. Ninety per cent of ectopic pancreas is found in the stomach, duodenum, and jejunum. Mostly it is asymptomatic and benign. For this reason, therapy is indicated only in patients with symptoms such as pyloric obstruction, bleeding, and malignant transformation. Surgical resection or endoscopic mucosal resection as a newer method are recommended.

show abstract

Anaplastic Carcinoma Arising in Ectopic Pancreas Located in the Distal Esophagus

Cited by 32 publications

References 4 publications

Anaplastic Carcinoma Possibly Arising from a Heterotopic Pancreas

Anaplastic Carcinoma Possibly Arising from a Heterotopic Pancreas

Adenocarcinoma arising in association with gastric heterotopic pancreas: A case report and review of the literature

Heterotopes Pankreasgewebe in der Gallenblase

Contact Info

Product

Resources

About