Anaplasic large cells lymphoma associated with breast implants

Batista, Bernardo Nogueira

doi:10.29289/259453942018edit296

Cited by 1 publication

(4 citation statements)

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“…A literature review found five previous publications that included the diagnosis of BIA-ALCL in a Brazilian national. 7,[9][10][11]13 These publications included a total of 15 patients with BIA-ALCL and are summarized in Table 1. Although no clinical results are reported in 10 of these cases, 7 this brought the total number of published BIA-ALCL cases in Brazil to 29.…”

Section: Resultsmentioning

confidence: 99%

“…7,[9][10][11]13 These publications included a total of 15 patients with BIA-ALCL and are summarized in Table 1. Although no clinical results are reported in 10 of these cases, 7 this brought the total number of published BIA-ALCL cases in Brazil to 29. Using available and extrapolated breast implant patient statistics for cosmetic augmentation and reconstruction, an estimated 2,193,803 Brazilian women currently have breast implants 6,14-18 (Table 2).…”

Section: Resultsmentioning

confidence: 99%

“…25 Meanwhile, a total of 29 cases have been reported in Brazil, including the 14 cases reported for the first time in this study. 7,9–11,13,26 With a reported incidence between one in 355 5 and one in 36,730, depending on the implant manufacturer 4,27 (Silimed polyurethane, one in 2596; Biocell, one in 3194; Nagor, one in 6024; Siltex, one in 36,730), we expect a much larger prevalence of the disease. Even for the Paraná state, with 10 million inhabitants, 14 BIA-ALCL cases seem to represent only a small portion of the potential case burden in the local population.…”

Section: Discussionmentioning

confidence: 99%

“…Few cases of BIA-ALCL in the Brazilian population have been reported in the medical literature. [7][8][9][10][11] The purpose of this article is to present the first prospective registry of BIA-ALCL in the Brazilian population using a process developed by a local task force to increase awareness, diagnosis, and registration, and analyze outcomes of published national cases.…”

mentioning

confidence: 99%

See 3 more Smart Citations

“Breast Implant-Associated Anaplastic Large Cell Lymphoma in Brazil: What Are We Missing?”

Groth

Clemens

Graf

et al. 2022

Plastic &Amp; Reconstructive Surgery

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Background: Breast implant–associated anaplastic large-cell lymphoma (BIA-ALCL) has been diagnosed in more than 1000 patients in more than 30 countries, although only a few cases have been reported in Latin America and the Caribbean to date. As the second-largest global market for breast implants with a predominance of textured-surface implants, Brazil is a major global market for cosmetic augmentations, making it unlikely that cases of BIA-ALCL are actually scarce. Methods: A local and voluntary registry of patients with BIA-ALCL was initiated in 2018. All patients diagnosed with BIA-ALCL were confirmed by the World Health Organization criteria. Implant characteristics, disease symptoms, treatment, and oncologic outcomes were assessed. Results: Fourteen cases of BIA-ALCL in a Brazilian population were identified in the Paraná state. Disease-specific diagnostic tests were omitted before surgical intervention in 50 percent of patients. With additional cases from a literature review, the treatment and outcomes of 29 cases of BIA-ALCL in Brazil were assessed. Conclusions: Compared with other populations, these initial observations suggest that awareness of the disease by the local breast surgery community remains low and that a number of cases may remain undiagnosed. Lack of preoperative diagnostic testing compromises disease treatment, oncologic outcomes, and both short- and long-term surveillance.

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