Anaphylaxis to topical bacitracin zinc ointment

Saryan, John A.; Dammin, Tristram C.; Bouras, Athanasios E

doi:10.1016/s0735-6757(98)90005-5

Cited by 41 publications

(16 citation statements)

References 10 publications

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“…In three patients who were patch test positive to bacitracin, Bjorkner and Möller 70 reported that bacitracin injection caused a local wheal-and-flare reaction. Severe life-threatening anaphylactic shock from topical administration of bacitracin has also been reported after application to stasis ulcers, 168,171 atopic dermatitis, 170 recent tattoos, 169 abrasions, 172 and intraoperatively when used in irrigation. 173,174 Baes 82 reported an interesting case suggesting topical sensitization to virginiamycin with a subsequent type I reaction to systemic administration of pristinamycin.…”

Section: Type I Hypersensitivitymentioning

confidence: 99%

“…173,174 Baes 82 reported an interesting case suggesting topical sensitization to virginiamycin with a subsequent type I reaction to systemic administration of pristinamycin. A 44-year-old male applied a virginiamycin-containing salve for a presumed bacterial 169 Tattoo A Roupe 170 Atopic dermatitis A Schecter 171 Ulcer A Sarayan 172 Abrasions A Bacitracin irrigation Blas 173 Intraoperative A Sprung 174 Intraoperative A Bacitracin and neomycin Goh 175 Burn A/CU Bacitracin/polymyxin B Eedy 176 Ulcer CU Benzoyl peroxide Minciullo 108 Acne CU Tkach 186 Acne/abrasive scrub CU Clioquinol Katsarou Van Ketel 179 reported a 7-year-old girl who developed contact urticaria after the application of an erythromycin stearate suspension for treatment of bronchitis. She developed a generalized urticarial eruption and the treatment was discontinued.…”

Section: Type I Hypersensitivitymentioning

confidence: 99%

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Allergic contact dermatitis to topical antibiotics: Epidemiology, responsible allergens, and management

Gehrig

Warshaw

2008

Journal of the American Academy of Dermatology

130

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Section: Type I Hypersensitivitymentioning

confidence: 99%

Section: Type I Hypersensitivitymentioning

confidence: 99%

Allergic contact dermatitis to topical antibiotics: Epidemiology, responsible allergens, and management

Gehrig

Warshaw

2008

Journal of the American Academy of Dermatology

130

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“…8 Importantly, petrolatum rarely induces allergic contact dermatitis (ACD) reactions 9 and has never been reported to cause contact anaphylaxis, whereas bacitracin was shown to induce ACD in up to 13% of patients 10 and has caused contact anaphylaxis in several cases. [11][12][13][14][15] However, the molecular changes induced by petrolatum are unknown.…”

mentioning

confidence: 99%

Petrolatum: Barrier repair and antimicrobial responses underlying this “inert” moisturizer

Czarnowicki

Malajian

Khattri

et al. 2016

Journal of Allergy and Clinical Immunology

132

108

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“…Clinical features occur shortly after administration and can include pruritus, urticaria, dyspnea, throat swelling, nausea, diarrhea, dizziness, and death. 143,144 Treatment of anaphylaxis is emergent and includes epinephrine, corticosteroids, and antihistamines. 143 Chemical burns have occurred from prolonged contact with povidone-iodine in whirlpool baths and soaks or under an occlusive device or dressing.…”

Section: Identification Of Infection and Adverse Reactionsmentioning

confidence: 99%

“…143,144 Treatment of anaphylaxis is emergent and includes epinephrine, corticosteroids, and antihistamines. 143 Chemical burns have occurred from prolonged contact with povidone-iodine in whirlpool baths and soaks or under an occlusive device or dressing. 163 Povidone-iodine has also been associated with metabolic acidosis, cardiovascular instability, renal insufficiency, and death when used indiscriminately for large wounds.…”

Section: Identification Of Infection and Adverse Reactionsmentioning

confidence: 99%

National Athletic Trainers' Association Position Statement: Management of Acute Skin Trauma

Beam

Buckley

Holcomb

et al. 2016

Journal of Athletic Training

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Objective: To present recommendations for the cleansing, debridement, dressing, and monitoring of acute skin trauma in patients.Background: Acute skin trauma is common during participation in athletic and recreational activities. Clinical decisions and intervention protocols after injury vary among athletic trainers and are often based on ritualistic practices. An understanding of cleansing, debridement, and dressing techniques; clinical features of infection and adverse reactions; and monitoring of acute skin trauma is critical for certified athletic trainers and other allied health and medical professionals to create a local wound environment that promotes healing and lessens the risk of complications.Recommendations: These guidelines are intended to provide the certified athletic trainer and others participating in athletic health care with specific knowledge about and recommendations for the management of acute skin trauma.Key Words: abrasions, avulsions, blisters, incisions, lacerations, punctures, cleansing, debridement, nonocclusive dressings, occlusive dressings, infection, adverse reactions T raumatic injury to the skin is common among athletes participating in all sports.1 The exact frequencies of abrasions, avulsions, blisters, incisions, lacerations, and punctures are difficult to calculate because many patients do not seek medical attention after injury; for others, their activity level is initially unaffected, and the injury is not recorded on surveillance reports. Unreported skin trauma and inappropriate wound management can result in delayed healing, cross-contamination, bacterial colonization, and infection, adversely affecting the overall health and playing status of the patient. Managing acute skin trauma through appropriate cleansing, debridement, and dressing techniques can create an environment conducive to healing and lessen the risk of complications. 2,3Wound-management techniques have undergone drastic changes over the last 50 years, and other allied health care professions, organizations, and facilities have developed guidelines that serve as standards of care. [4][5][6] However, guidelines for the management of acute skin trauma by athletic trainers (ATs) are limited in the literature.1,7 The development and implementation of cleansing, debridement, and dressing techniques for acute skin trauma are critical for ATs to successfully deliver health care services to patients. The following review and recommendations provide information on the management of acute skin trauma and guidelines for ATs and other allied health and medical professionals who care for patients. RECOMMENDATIONSThis position statement is based on current research and literature with regard to the cleansing, debridement, dressing, and monitoring of acute skin trauma. We independently categorized the studies and literature using the Strength of Recommendation Taxonomy (SORT) developed by the American Academy of Family Physicians. 8 The taxonomy grades the quality of the data from the literature (level of evidence) and p...

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Anaphylaxis to topical bacitracin zinc ointment

Cited by 41 publications

References 10 publications

Allergic contact dermatitis to topical antibiotics: Epidemiology, responsible allergens, and management

Allergic contact dermatitis to topical antibiotics: Epidemiology, responsible allergens, and management

Petrolatum: Barrier repair and antimicrobial responses underlying this “inert” moisturizer

National Athletic Trainers' Association Position Statement: Management of Acute Skin Trauma

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