Anaphylaxis during anesthesia in France: An 8-year national survey

Mertès, Paul-Michel; Alla, François; Tréchot, P.; Auroy, Yves; Jougla, Éric

doi:10.1016/j.jaci.2011.03.003

Cited by 355 publications

(288 citation statements)

References 48 publications

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“…In France, there is a well-established network of clinics (GERAP) dedicated to the investigation of peri-operative anaphylaxis using a standardised protocol [16]. Both our study and the above French study (Dong et al) showed that although neuromuscular blocking drugs were still the major cause of IgE-mediated reactions, they accounted for an lower proportion of cases from 1993 to 2012 [15][16][17][18][19]. This trend is similar to that reported by investigators in Australia, who found that neuromuscular blocking drugs accounted for 38% of cases [20].…”

Section: Discussionmentioning

confidence: 72%

Anaesthesia-associated hypersensitivity reactions: seven years' data from a British bi-specialty clinic

McEwan

Karanam

et al. 2015

Anaesthesia

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SummaryOur bi-specialty clinic was established to systematically investigate patients with suspected peri-operative hypersensitivity reactions. Four hundred and ten patients were studied; 316 following an intra-operative reaction ('postoperative' group) and 94 with a previous history of reaction, referred before undergoing anaesthesia ('pre-operative' group). In the postoperative group, 173 (54.7%) were diagnosed with IgE-mediated reactions: 65 (37.6%) to neuromuscular blocking drugs; 54 (31.2%) antibiotics; 15 (8.7%) chlorhexidine and 12 (6.9%) patent blue dye. Reactions were severe in 114 patients (65.9%). All reactions to patent blue dye were severe. We identified IgE sensitisation in 22 (13.2%) cases with isolated mucocutaneous reactions. Only 173 (54.7%) patients had serum tryptase samples taken. Referrers' suspected causal agent was confirmed in only 37.2% of patients. Of 94 patients reviewed 'pre-operatively', 29 (30.8%) were diagnosed with IgE-mediated hypersensitivity reactions, reinforcing the importance of investigating this group of patients. Knowledge of the range of causative agents identified in our study should guide the investigation of suspected peri-operative hypersensitivity reactions.

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Section: Discussionmentioning

confidence: 72%

Anaesthesia-associated hypersensitivity reactions: seven years' data from a British bi-specialty clinic

McEwan

Karanam

et al. 2015

Anaesthesia

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“…Specific investigation should therefore be conducted 4 to 6 weeks after the reaction and relies on skin tests, serum-specific IgE, and challenge procedures [1,4].…”

Section: Discussionmentioning

confidence: 99%

“…Anaphylaxis during general anaesthesia is a rare but life-threatening clinical condition involving multiple organ systems, and this terminology is usually used when the allergic reaction is associated with cardiovascular collapse or airway obstruction, with or without cutaneous manifestations [3]. Epidemiological studies report a variable incidence of one allergic reaction in 4.000 to 25.000 anesthetic procedures, with overall mortality rate ranging from 0.001% to 9% [1,[4][5][6][7][8][9].…”

Section: Introductionmentioning

confidence: 99%

Hypersensitivity Reactions During Anaesthesia Care: An 11-Year Experience From A Tertiary Hospital

Pereira¹,

Almeida²,

Frada³

et al. 2017

J Anesth Clin Res

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Introduction: Anaphylaxis during general anaesthesia is a rare but life-threatening clinical condition involving multiple organ systems, with a reported incidence of 1 in 4.000 to 25.000 anesthetic procedures. The objective of this study is to describe the experience of a Tertiary University Hospital with drug hypersensitivity reactions, including anaphylaxis, during anaesthesia care, their main causal agents, treatment and investigation.

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“…According to a study published in the Journal of Allergy and clinical Immunology in 2016 reviewing the incidence of adverse drug reactions in anesthesia over an eight-year period, an IgE mediated drug hypersensitivity reaction most commonly presents with cardiovascular symptoms in 84% of cases which include hypotension or cardiovascular collapse, and cutaneous symptoms (70% of cases). These symptoms can be differentiated from MTS by the presentation of angioedema (11%), urticarial (20%), bronchospasm (41%), increased levels of tryptase (45%), and previously described drug (18%) and food intolerances (8.5%) [7].…”

Section: Diagnosis Of Mesenteric Traction Syndrome and Differential Dmentioning

confidence: 99%

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2017

JACCOA

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The first time I heard of mesenteric traction syndrome was three years into my training as an anesthesia resident. This first time was unfortunately intraoperatively while my patient was acutely unstable and mesenteric traction syndrome was part of my anesthesia team's differential diagnosis. Following this event I set out to educate myself about mesenteric traction syndrome and was shocked to find there was very little mention of it in the anesthesia literature, especially common textbooks that I had used throughout my residency to educate myself. The goal of this article is to present the literature on mesenteric traction that I encountered during my research and to provide a thorough review of the consensus on the etiology, pathophysiology, prevention and treatment of mesenteric traction syndrome. At the end of the review, I examine areas of mesenteric traction that need further investigation in order to fully understand mesenteric traction syndrome and what we can do, as anesthesiologists, to prevent it and appropriately treat it.

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Anaphylaxis during anesthesia in France: An 8-year national survey

Cited by 355 publications

References 48 publications

Anaesthesia-associated hypersensitivity reactions: seven years' data from a British bi-specialty clinic

Anaesthesia-associated hypersensitivity reactions: seven years' data from a British bi-specialty clinic

Hypersensitivity Reactions During Anaesthesia Care: An 11-Year Experience From A Tertiary Hospital

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