Anaphylaxis after consumption of pumpkin seeds in a 2-y-old child tolerant to its pulp: A case study

Protein contact dermatitis to a tan‐extender lotion: Imputability of pumpkin seed oil (Luffa cylindrica seed oil)

“…Allergy to pumpkin is a very rare disorder and only few isolated case reports have been reported 4,5 . All parts of the fruit can be responsible for allergic symptoms.…”

“…Allergy to pumpkin is a very rare disorder and only few isolated case reports have been reported. 4,5 All parts of the fruit can be responsible for allergic symptoms. Patients allergic to seeds usually tolerate pumpkin pulp and other fruits of the cucurbitaceous family (cucumber, melon and/or watermelon) but may have allergy to other seeds (sunflower and poppy seeds).…”

“…6 Homology between amino-acid sequences in storage proteins may indicate cross-reactivity between different edible seeds, peanuts and tree nuts. [4][5][6] Although pumpkin allergy usually develops after consumption, reports suggest the possibility of exposure through skin contact and/or inhalation of raw pumpkin or pumpkin seed allergens. 4,7,8 As Luffa Cylindrica seed oil is widely used in cosmetics, physicians should be aware of this potential allergen through pumpkin seeds.…”

“…Homology between amino‐acid sequences in storage proteins may indicate cross‐reactivity between different edible seeds, peanuts and tree nuts 4–6 …”

New arrivals in anaphylaxis to foods

“…In the EU, only sesame and mustard seed have to be included as an allergen on food labels, however, other seeds such as pumpkin, sunflower, flaxseed and pine nuts are increasingly being utilised in breakfast cereals, biscuits, crackers and protein powders. Case reports of pumpkin seed allergy usually find that the pumpkin flesh is tolerated but not the seeds [53]. A review of four patients reacting to pumpkin seeds but not the pulp, identified two allergens, although only Cuc ma 5 (2S albumin) was positive in all four cases [54].…”