Anaphylactoid reactions with gastrointestinal contrast media.

Skucas, Jovitas

doi:10.2214/ajr.168.4.9124150

Cited by 45 publications

(20 citation statements)

References 16 publications

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“…Overall, gastrografin has adverse effects in 5-7% of cases, mostly related to minor reactions well tolerated by patients (metallic taste, nausea and vomiting, rash, or dryness of mucosa), with a mortality rate of 0.01% [24] . However, severe anaphylactic reactions, electrolyte imbalance, and aspiration pneumonia represents the most serious complications, though they did not reach 2% of cases [25] .…”

Section: Discussionmentioning

confidence: 99%

Adhesive Small Bowel Obstruction: Predictive Factors of Lack of Response in Conservative Management with Gastrografin

Bueno-Lledó¹,

Barber²,

Vaqué³

et al. 2015

Dig Surg

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Background: Gastrografin represents a useful tool in the diagnosis and management of adhesive small bowel obstruction (ASBO). The aim of this study is to identify variables with negative influence in nonoperative management with gastrografin. Methods: From August 2008 to March 2013, 223 consecutive patients with 235 episodes of ASBO were included and received gastrografin. A protocol for prospective data collection was developed. In order to explore factors related to the failure of nonoperative treatment, univariate and multivariate analysis were performed. Results: One hundred and ninety eight episodes responded to nonoperative treatment (84.2% of success) and 33 patients (15.8%) required surgical intervention. Only 3 patients of the gastrografin cohort with contrast in colon, required surgery. Predictive factors of failure of nonoperative management with gastrografin were patients aged above 65 (p = 0.01; OR 1.791, 95% CI 1.41-2.19), with a history of 2 or more previous laparotomies (p = 0.03; OR 2.91, 95% CI 2.19-3.71), and who had undergone previous abdominal surgery due to ASBO (p = 0.002; OR 1.381, 95% CI 1.10-1.79). Conclusion: Patient age, the number of previous laparotomies, and the fact that previous abdominal surgery was conducted due to ASBO are indicative of unsuccessful management with gastrografin.

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Section: Discussionmentioning

confidence: 99%

Adhesive Small Bowel Obstruction: Predictive Factors of Lack of Response in Conservative Management with Gastrografin

Bueno-Lledó¹,

Barber²,

Vaqué³

et al. 2015

Dig Surg

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“…The administration of hyperosmolar iodine-based regimens provides instead a homogeneous tagging of both the fluid and solid residue, and determines fluid secretion into the colon, thus creating a smooth liquid-to-air interface that improves the performance of digital subtraction software [14]. However, oral iodine administration may cause adverse events, such as nausea, vomiting, skin eruptions [17,18] and hyperosmolar diarrhea occurs in approximately 10% of cases [11].…”

Section: Introductionmentioning

confidence: 99%

Comparison of three different iodine-based bowel regimens for CT colonography

Campanella

Morra²,

Delsanto³

et al. 2009

Eur Radiol

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“…Some authors suggested that Gastrografin (Schering, Berlin, Germany) promoted the resolution of obstruction (14)(15)(16)(17)(18), but its efficacy is still questionable and controversial and some rare complications associated with Gastrografin including anaphylactic reaction and lethal aspiration are reported (19,20).…”

Section: Discussionmentioning

confidence: 99%