Analyzing the mechanism by which oyster peptides target IL-2 in melanoma cell apoptosis based on RNA-seq and m6A-seq

Abstract

Melanoma is a kind of skin cancer with high malignancy and strong proliferation and invasion abilities. Chemotherapy drugs in the clinic have the disadvantages of high price and high toxicity....

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“…The results of this analysis revealed that Kaempferol has a mass (286), number of hydrogen bond donors (4), number of hydrogen bond acceptors (6), log P (2.305), and molar reactivity (72.385). These characteristics provide information on the physicochemical properties of Kaempferol, which are important in the evaluation of the pharmacokinetic potential and availability of the drug in potential clinical applications [48][49][50]. Table 2 presents the data from Lipinski and Figure 2 depicts the results of the Tyr and 3awu interactions.…”

Interaction of Masilinic Acid from Clove Plant (Syzygium aromaticum) with CD81 Antigen in Inhibiting HIV Virus Regulation In Silico

“…Therefore, these findings strengthen the argument that Masilinic Acid can interact with the CD81 antigen and potentially inhibit the HIV infection process. [31][32][33][34] Figure 1 shows the visualization results of Masilinic Acid and the CD81 antigen in Protein Plus.…”

In Silico Study on the Inhibition of Sitogluside from Clove Plant (Syzygium aromaticum) on Interleukin 2 in B and T Cell Proliferation

“…In PyMol, these components can be removed to purify the protein. [30][31][32] Furthermore, proteins sometimes have more than one conformation or chain. In this scenario, the researcher needs to select which conformation or chain is most relevant to their docking study.…”