Due to the COVID-19 epidemic, many countries have taken a number of epidemic prevention and control measures, which have had a huge impact on the global economy. This paper studies the major issues facing the global economy after the relaxation of epidemic control policies, such as economic recession, inflation, debt crisis and energy crisis, and countermeasures. In this paper, corresponding countermeasures are proposed to address economic recession, including increasing government spending, reducing taxes, lowering interest rates, and increasing the money supply and to address the inflation, including reducing government spending, increasing taxes, raising interest rates, and reducing the money supply. In response to the debt crisis, corresponding countermeasures have been proposed from the aspects of strengthening government supervision, adjusting government expenditures, tax rates, interest rates, and money supply. In the light of the energy crisis, this paper puts forward corresponding countermeasures from aspects of improving energy utilization efficiency, reducing energy consumption, developing green energy that can replace traditional energy, and strengthening the supervision of the energy market.