Analyzing Cell-free Genomic DNA in Spent Culture Media: Noninvasive Insight into the Blastocysts
Siddhartha Shankar Layek,
Shrushti Kanani,
Shilpa Doultani
et al.
Abstract:A commonly accepted standard protocol for noninvasive techniques for the genetic evaluation of an embryo remains elusive due to inconclusiveness regarding the volume of spent media to be acquired and the possibility of acquiring the same for subsequent analysis. Single embryo culture is imperative for standardizing noninvasive preimplantation testing using cell-free DNA (cf-DNA) released by individual developing embryos. This study aims to compare the development dynamics of single-drop embryonic culture again… Show more
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