Analytical techniques for trace organic compounds - VI. Application of liquid chromatography-mass spectrometry (Technical Report)

Abstract

Names of countries given after Members' names are in accordance with the IUPAC Handbook 1991-93; changes will be effected in the 1994-95 edition. Abstract -The development of combinations of liquid chromatography with mass spectroemtry in an on line fashion has come to a stage where such combinations become part of routine procedures for the analysis of a broad variety of samples. Since several technically very different interfaces have been devised in recent years, the major types are briefly discussed, even though it becomes more and more clear that only a few will survive. The most outstanding device appears to be the atmospheric pressure sources with electrospray and chemical ionization, since it covers many areas of chemical analysis in terms of polarity, lability and molecular weights. The attempt has been made not only to give a picture of the techniques, but to indicate by means of a few examples, how useful the different devices are and where they are at their limits. Furthermore, the criteiia are indicated which may be applied to make a choice on the basis of analytical requirements and technical and financial possibilities.

Mass Spectrometry in Environmental Sciences

“…57 In 1999, Niessen published an overview of the state-of-the-art in LC/MS. 58 Several general overviews of LC/MS applications were also published, [59][60][61][62] and earlier reviews in 1991-1996 covered environmental applications of thermospray and particle beam-LC/MS. [63][64][65][66][67] Van Emon and Lopez-Avila published a review on immunoaffinity extraction with on-line LC/MS, which included applications to several environmental pollutants.…”

“…In 1999, Niessen published an overview of the state-of-the-art in LC/MS . Several general overviews of LC/MS applications were also published, − and earlier reviews in 1991−1996 covered environmental applications of thermospray and particle beam-LC/MS. − Van Emon and Lopez-Avila published a review on immunoaffinity extraction with on-line LC/MS, which included applications to several environmental pollutants . Other reviews included environmental applications of membrane introduction mass spectrometry (MIMS), , CE/MS, − CE/ICP-MS, GC/MS, , GC/infrared spectroscopy (IR) and GC/MS, electron-capture (EC)-MS, and chemical ionization (CI)-MS .…”

Liquid chromatography–mass spectrometric analysis of phenylurea herbicides and their degradation products using an atmospheric pressure ionization interface

“…3,4 LC-MS is a useful technique for the selective and sensitive determination of nonvolatile compounds and its application to environmental analyses has been developed. 5,6 Some articles have reported LC-MS of phenylurea herbicides using particle beam, 7 thermospray 8-10 and electrospray 11 interfaces.…”