Ion exchange separation of rhenium using Purolite A-170 and Purolite A-172 was carried out from the dust leach solution of molybdenite concentrate. Different parameters such as effect of contact time, equilibrium pH, and solid liquid ratio were investigated. The optimum absorption condition for Purolite A-172 resin was determined, and the absorption efficiency of Re and Mo were obtained to be about 90 and 0%, respectively. From results, it was evident that, the performance of Purolite A-172 resin was more effective than Purolite A-170 resin, towards the selective recovery of Re from the molybdenite dust leach solution.