I. Introduction Advanced missile control designs have been founded on recent developments aimed at a more streamlined engineering design approach to improve performance and cost of design. Central to these developments is the attempt for a full integration of subsystems to exploit any potential synergy. In missile control, much effort has been concentrated on integrating the autopilot and guidance subsystems [1, 2]. Such a unification of the control algorithm has direct benefits for the performance of the missile, primarily by removing the previously existing lag between the commanded and tracked acceleration from guidance and autopilot, respectively [3]. Several strategies have been proposed following this integrated control outlook, including sliding mode control [4, 5, 6], state feedback regulators [7, 8], as well as model-based approaches, for instance, a recently proposed linear quadratic regulation with model bias [9]. Model predictive control (MPC) is recognized for its ability in handling nonlinearities and constraints, therefore it is suited for high-performing agile missiles operated near constraints. This is demonstrated, for example, by the fact that the predominant proportional navigation (PN) in missile guidance is based on linear quadratic regulation [10], which is a special case of model-predictive control where constraints are absent and linear prediction model is used. Furthermore, the performance and feasibility of model-predictive missile autopilot has been studied in [11, 12]. Although promising a superior performance, MPC is typically associated with high levels of computational cost. Therefore, prior to the real-time realization of MPC, it is important to know the required computational capacity to implement MPC, especially in applications involving fast sampling rates such as missile control. A comprehensive offline tuning of MPC that balances both performance and cost is therefore needed before the implementation. In light of this, as a natural tuning method for an integrated autopilot and guidance algorithm, a multi-objective design approach that considers both closed-loop performance and required computational capacity allows for the comprehensive consideration of both algorithm and implementation designs of the system. A coupled approach in control tuning is known to be valuable due to its potential in streamlining the design process and produce system-optimal designs [13]. This allows for a more comprehensive analysis, such as the optimization of multiple underlying tuning/design objectives along with constraints, as introduced and discussed in [14]. This notion