Analytical methods for the determination of arsenosugars—A review of recent trends and developments

Niegel, Claudia; Matysik, Frank‐Michael

doi:10.1016/j.aca.2009.10.041

Cited by 60 publications

(87 citation statements)

References 136 publications

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“…General separation aspects A mixture containing the four arsenic species AsB, AsC, AsS-OH and AsS-SO 4 (Fig. 1) and caffeine as EOF marker was analyzed using short capillaries with small IDs (25 mm and 50 mm).…”

Section: Resultsmentioning

confidence: 99%

“…Limits of detection (LODs) were determined to be 3 times the signal-to-noise ratio (S/N). LODs were 160 mg L À1 As for AsC, 180 mg L À1 As for AsC, 125 mg L À1 As for AsS-OH and 790 mg L À1 As for AsS-SO 4 . Relative standard deviations (RSDs) of peak heights for consecutive injections (AsS-OH, 3 mg L À1 As; AsS-SO 4 , 6.5 mg L À1 As) ranged between 13 and 17% (29.5 cm capillary, n ¼ 8) and 14 and 29% (27 cm capillary, n ¼ 9).…”

Section: Fast Separation Of Arsenic Species In Aqueous Buffersmentioning

confidence: 98%

“…However, this did not improve the separation and detection of AsS-SO 4 (results not shown) and was not further evaluated.…”

Section: Fast Separation Of Arsenic Species In Aqueous Buffersmentioning

confidence: 99%

“…The overall acid-base property of a molecule is primarily determined by the functional groups in the aglycone. 34 The sulfuric acid ester moiety in the side chain of AsS-SO 4 shows a strong acidic property. Thus, at pH 3 this arsenosugar is separated from the neutral EOF marker.…”

Section: Fast Separation Of Arsenic Species In Aqueous Buffersmentioning

confidence: 99%

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Fast separations by capillary electrophoresis hyphenated to electrospray ionization time-of-flight mass spectrometry as a tool for arsenic speciation analysis

Niegel

Pfeiffer

Grundmann

et al. 2012

Analyst

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Fast capillary electrophoresis (CE) hyphenated to time-of-flight mass spectrometry (TOF-MS) of four organoarsenic species (glycerol oxoarsenosugar, sulfate oxoarsenosugar, arsenobetaine, arsenocholine) are presented using short length CE capillaries under high electric field strengths of up to 1.3 kV cm À1 with small inner diameter (ID). The separation of arsenosugars by CE is demonstrated for the first time. An aqueous formic acid solution was employed as the background electrolyte (BGE) for the separation. Various acid concentrations were evaluated for their influence on migration times, separation efficiency as well as with regard to controlling the charge of the arsenic species. A 0.1 M formic acid/ammonium formate buffer (pH 2.8) proved to be suitable for the separation of the four species. A non-aqueous BGE was tested as an alternative buffer system for fast speciation analysis. Separation of arsenobetaine and arsenocholine could even be achieved within 10 s by pressure-assisted CE. Application of the optimized method for the analysis of extracts of a seagrass and a Wakame algae sample as well as the brown algae homogenate reference material IAEA-140/TM revealed a clear signal for the glycerol arsenosugar.

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Section: Resultsmentioning

confidence: 99%

Section: Fast Separation Of Arsenic Species In Aqueous Buffersmentioning

confidence: 98%

“…However, this did not improve the separation and detection of AsS-SO 4 (results not shown) and was not further evaluated.…”

Section: Fast Separation Of Arsenic Species In Aqueous Buffersmentioning

confidence: 99%

Section: Fast Separation Of Arsenic Species In Aqueous Buffersmentioning

confidence: 99%

See 2 more Smart Citations

Fast separations by capillary electrophoresis hyphenated to electrospray ionization time-of-flight mass spectrometry as a tool for arsenic speciation analysis

Niegel

Pfeiffer

Grundmann

et al. 2012

Analyst

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“…Arsenosugars, a kind of As-containing carbohydrates, widely present in freshwater, marine biota and terrestrial organism. A comprehensive introduction of the method for sample pre-treatment, extraction, separation and detection of arsenosugars can be found in a recent review [18].…”

Section: Speciation Of Asmentioning

confidence: 99%

Recent advances in speciation analysis of mercury, arsenic and selenium

2012

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Mercury (Hg), arsenic (As) and selenium (Se) are ubiquitous in the environment and exist in a variety of species, which have great influence on their transport, bioaccumulation and toxicity. This review presents the recent research progress in speciation analysis of Hg, As, and Se, with emphasis on enhanced cold vapor generation as interface for liquid chromatography and atomic spectrometry, speciation of volatile species in gas phase, and isotope dilution technique to improve the precision and accuracy of speciation. Hyphenated techniques to characterize the complexes of Hg and As with phytochelatins and chromatographic separation coupled with multi-collector-inductively coupled plasma mass spectrometry to measure species-specific isotopic ratios, are also briefly discussed. Mercury (Hg) and arsenic (As) are among the most highly toxic elements for humans and ecosystems and can cause serious environmental and human health problems even at low concentrations [1,2]. Selenium (Se) is an "essential toxin" for human health. It has been recognized as an important antioxidant and anti-cancer element. However, Se can also pose negative impact such as defective skin and hair loss [3]. The adsorption/uptake, transport, bioaccumulation, metabolism and toxicity of these elements strongly depend on their chemical species present in environmental and biological samples. In the environment, one species can transform to another through chemical or biological processes. For example, in anaerobic sediments, sulfur-reducing or iron-reducing bacteria can methylate inorganic mercury into highly toxic methylmercury (MeHg) [4,5]. Therefore, speciation analysis of Hg, As and Se is of great importance in order to elucidate the biogeochemcal cycle and toxicology of these elements. Speciation analysis mainly involves chromatographic separation (gas chromatography (GC) or high performance liquid chromatography (HPLC)) hyphenated with element-specific spectrometry or molecular mass spectrometry. This review presents the recent advances in speciation analysis of Hg, As, and Se based on chromatographic separation, with emphasis on enhanced cold vapor generation (CVG) as interface for LC and atomic spectrometry, speciation of volatile Hg, As and Se in gas phase, and isotope dilution technique to improve the precision and accuracy of speciation. Hyphenated techniques to characterize the complexes of Hg and As with phytochelatins and chromatographic separation coupled with multi-collector-inductively coupled plasma mass spectrometry (MC-ICP-MS) to measure species-specific isotopic ratios, are also briefly introduced.

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Methodological aspects of speciation analysis in food products

Wróbel¹,

Wróbel²

2015

Handbook of Mineral Elements in Food

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Analytical methods for the determination of arsenosugars—A review of recent trends and developments

Cited by 60 publications

References 136 publications

Fast separations by capillary electrophoresis hyphenated to electrospray ionization time-of-flight mass spectrometry as a tool for arsenic speciation analysis

Fast separations by capillary electrophoresis hyphenated to electrospray ionization time-of-flight mass spectrometry as a tool for arsenic speciation analysis

Recent advances in speciation analysis of mercury, arsenic and selenium

Methodological aspects of speciation analysis in food products

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