Analytical methods for Ebola virus detection

Sharma, Pramod; Suleman, Shariq; Farooqui, Asim; Ali, Wajid; Narang, Jagriti; Malode, Shweta J.; Shetti, Nagaraj P.

doi:10.1016/j.microc.2022.107333

Cited by 6 publications

(1 citation statement)

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“…These matrix proteins are important for the structure and stability of the viral lipid coat. A desirable target for the development of EBOV therapies is this distinct EBOV replication cycle 23 . Immune Response Towards the EBOV: The struggle between the virus's ability to evade host immune responses and the host's ability to limit the virus reproduction determines the viral infection in any host.…”

Section: Replication Cycle Of Ebovmentioning

confidence: 99%

Resurgence of Ebola Virus: Transmission, Pathogenesis, Prevention and Cure

Aljowaie¹

2023

PJMHS

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Ebola virus (EBOV) disease is a zoonotic disease that is caused by four species of genus Ebolavirus. The EBOV disease has outbreaks (1976-2022) in West and Central African countries, high mortality rate has made it a public health concern. EBOV is a filamentous virus having negative stranded and non-segmented RNA. The EBOV genome has the unique capability of forming soluble glycoprotein. Since its first emergence in human history, several effective therapeutics and vaccines are developed. These vaccines include replicative or non-replicative vectored vaccines, DNA vaccines and monovalent or polyepitopic vaccines. This article reviewed the structure of EBOV and pathophysiology as well as the immune response of EBOV infection. In addition to diagnosis and vaccinations available to cure EBOV at acute and chronic stages. Keywords: Zoonotic disease, Filovirus, Soluble glycoprotein, DNA vaccines, Polyepitopic, Vectored vaccines, Pathophysiology, Immune response

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Section: Replication Cycle Of Ebovmentioning

confidence: 99%