Analytical dosimetric study of intensity-modulated radiotherapy (IMRT) and volumetric-modulated arc therapy (VMAT) for prostate cancer

Abstract

Purpose The study aimed to compare the dosimetric results and treatment delivery efficiency among four techniques to explore the preferred technique in prostate treatment. Materials and methods 7 IMRT, 9 IMRT, 1 ARC, and 2 ARC plans were created for 30 prostate cancer patients using the Eclipse™ treatment planning system (Varian Medical Systems). All the plans were designed to deliver 80.0 Gy in 40 fractions to the prostate planning target volume (PTV). Target coverage, organs at risk (OARs), number of monitor units, homogeneity, and conformity were compared across the four techniques to assess the quality of the plans. Results The study revealed better Planning Target Volume (PTV) dose coverage in the VMAT-2A than in the other plans. At the same time, VMAT-2A plans were found to be significantly lower in terms of Bladder and rectum doses than other techniques. In addition, VMAT has the advantage of considerably reducing the number of monitor units and treatment time. Conclusion For prostate cancer, VMAT may offer a favorable dose gradient profile, conformity, and MU and treatment time compared to IMRT.

A Novel Approach for Position Verification and Dose Calculation through Local MVCT Reconstruction

“…Intensity-modulated radiation therapy (IMRT) and volumetric-modulated arc therapy (VMAT) represent two advanced radiotherapy techniques that adjust radiation dose distribution to target tumor areas precisely while minimizing damage to healthy surrounding tissue. These two techniques have significantly improved treatment precision, reduced side effects, and enhanced patients’ quality of life [ 5 ]. IMRT and VMAT technologies have offered greater flexibility in radiation therapy, but have also introduced complexities in treatment planning and dose delivery [ 6 ].…”