This work presents new semi-analytical solutions for the combined fully-developed electro-osmotic (EO) pressure-driven flow in microchannels of viscoelastic fluids, described by the generalised Phan-Thien-Tanner model (gPTT) recently proposed by Ferrás et al. [Journal of Non-Newtonian Fluid Mechanics, 269: 88-99, 2019]. This generalised version of the PTT model presents a new function for the trace of the stress tensor -the Mittag-Leffler function -where one or two new fitting constants are considered in order to obtain additional fitting flexibility. The semi-analytical solution is obtained under sufficiently weak electric potentials that allows the Debye-Hückel approximation for the electrokinetic fields and for thin electric double layers.Based on the solution, the effects of the various relevant dimensionless numbers are assessed and discussed, such as the influence of εW i 2 , of the parameters α and β of the gPTT model, and also of κ, the dimensionless Debye-Hückel parameter. We conclude that the new model characteristics enhance the effects of both εW i 2 and κ on the velocity distribution across the microchannels. The effects of a high zeta potential are also studied numerically.