Abstract. For a closed, spin, odd dimensional Riemannian manifold pY, gq, we define the rho invariant ρ spin pY, E, H, rgsq for the twisted Dirac operator C E H on Y , acting on sections of a flat hermitian vector bundle E over Y , where H " ř i j`1 H 2j`1 is an odd-degree closed differential form on Y and H 2j`1 is a real-valued differential form of degree 2j`1. We prove that it only depends on the conformal class rgs of the metric g. In the special case when H is a closed 3-form, we use a Lichnerowicz-Weitzenböck formula for the square of the twisted Dirac operator, which in this case has no first order terms, to show that ρ spin pY, E, H, rgsq " ρ spin pY, E, rgsq for all |H| small enough, whenever g is conformally equivalent to a Riemannian metric of positive scalar curvature. When H is a top-degree form on an oriented three dimensional manifold, we also compute ρ spin pY, E, Hq.