Dark matter can be boosted by high energy particles in astrophysical environments through elastic scattering. We study the production of boosted dark matter via scattering with electrons in the relativistic jet of the closest active galactic nucleus, Centaurus A, and its detection in the Super-Kamiokande experiment. Since there are a huge number of electrons in the jet and dark matter is extremely dense around the supermassive black hole that powers the jet, the number of boosted dark matter is tremendously large. Compared to boosted dark matter from blazars, the dark matter flux from Centaurus A is enhanced due to the proximity of Centaurus A. The constraint on dark matter-electron scattering cross section set by Super-Kamiokande is more stringent, down to ∼ 10−36 cm2 for MeV dark matter.