2015
DOI: 10.1007/s10072-015-2347-2
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Analysis on therapeutic outcomes and prognostic factors of intracranial ependymoma: a report of 49 clinical cases in a single center

Abstract: Although intracranial ependymoma is relatively rare, it is often associated with great clinical aggressiveness and poor overall survival. There are controversies over factors affecting the prognosis of the disease. The aim of this retrospective study was to evaluate factors that may affect the therapeutic outcome and prognosis of intracranial ependymoma by reviewing the medical records of 49 patients who were surgically treated in our hospital between 2001 and 2014. Univariate and multivariate analyses were pe… Show more

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Cited by 3 publications
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“…The reported prognostic factors of ependymoma include age, tumor location, histological grade, the extent of resection (EOR), metastatic spread, Ki-67 status, and adjuvant radiotherapy (Metellus et al 2007;Kuncova et al 2009;Merchant et al 2009;Pejavar et al 2011;Tarapore et al 2013;Sayegh et al 2014). EOR is the most essential prognostic factor for ependymoma (Venkatramani et al 2013;Lin and Chintagumpala 2015;Ye et al 2015;Ramaswamy and Taylor 2016;Sato et al 2017;Jung et al 2018;Svoboda et al 2018). The Ki-67 protein is a biomarker for Liguo Wang and Song Han contributed equally to this work.…”
Section: Introductionmentioning
confidence: 99%
“…The reported prognostic factors of ependymoma include age, tumor location, histological grade, the extent of resection (EOR), metastatic spread, Ki-67 status, and adjuvant radiotherapy (Metellus et al 2007;Kuncova et al 2009;Merchant et al 2009;Pejavar et al 2011;Tarapore et al 2013;Sayegh et al 2014). EOR is the most essential prognostic factor for ependymoma (Venkatramani et al 2013;Lin and Chintagumpala 2015;Ye et al 2015;Ramaswamy and Taylor 2016;Sato et al 2017;Jung et al 2018;Svoboda et al 2018). The Ki-67 protein is a biomarker for Liguo Wang and Song Han contributed equally to this work.…”
Section: Introductionmentioning
confidence: 99%