Analysis on the Clinical Characteristics of 10 Cases of Asymptomatic SARS-CoV-2 Novel Coronavirus Infection

Abstract

Objective: To analyze the clinical features of asymptomatic patients infected with the SARS-CoV-2 novel coronavirus. Methods: The clinical data of 10 asymptomatic cases and 12 symptomatic cases of COVID-19 diagnosed during February 2020 to April 2020 was collected and the clinical features of the two groups of patients were compared. Results: 10 cases of asymptomatic infection and 12 cases of symptomatic patients were tested positive for the novel coronavirus nucleic acid test. There was no significant difference in gender distribution between the two groups (P?0.05); the average age of patients in the asymptomatic group was lower than that of the symptomatic group ( P?0.05), the difference in clinical classification between the two groups was statistically significant (P?0.05); there was no statistically significant difference in the results of chest CT examination involving lung lobes between the two groups (P?0.05), and there was no statistically significant difference in mortality between the two groups (P>0.05). Conclusion: The average age of asymptomatic novel coronavirus infections was lower than that of confirmed cases of COVID-19, mainly among young people. There was no significant difference in clinical classification, mortality and chest CT examination results between symptomatic and asymptomatic cases.

Vertical transmission of SARS‐CoV‐2: A prospective cross‐sectional study from a tertiary center

“…In many reports, no evidence of vertical transmission was found regarding various samples such as amniotic fluid, cord blood, neonatal throat glands, placental swabs, genital fluid, and breast milk samples in mothers infected with the virus. 13,14,[18][19][20] However, several studies exist in the literature reporting vertical transmission of SARS-CoV-2 through the placenta. [7][8][9][10] Although some show electronic microscopic changes, some have reported the presence of the SARS-CoV-2 genome in the placentas, especially in the term period.…”

Assessment of Maternal and Neonatal SARS-CoV-2 Viral Load, Transplacental Antibody Transfer, and Placental Pathology in Pregnancies During the COVID-19 Pandemic

“…[5][6][7] Data regarding the maternal immune response, vertical transmission, and placental infection have been limited largely to case reports, small case series, and systematic reviews. [8][9][10][11][12][13][14][15][16][17][18][19][20] Here, we report key biological data from a large prospective cohort study of SARS-CoV-2 infection in pregnancy regarding viral load, antibody response, transplacental antibody transfer, and placental pathology.…”

Intrauterine Vertical Transmission of SARS-CoV-2 Infection Among Confirmed Cases of Pregnant Women: “A Double Burden for the Pregnant Women”—A Systematic Review

“…87 The earliest study showed that the clinical features of infected pregnant women with this virus in late pregnancy were found to be similar to those of nonpregnant patients. 80 However, since the impact of this virus on pregnant women is still limited, they should be given a consideration including their newborns, about COVID-19 management and prevention means. 89 The pregnant mother must be focused as high-risk for COVID-19 and need to lessen the contact.…”

“…79 The earliest data have reported as there is no concrete evidence for vertical transmission of SARS-CoV-2 virus because of intrauterine infections. 52,[80][81][82][83][84][85][86][87][88] It will probably be a rare that fetuses will be uninfected at the time of their birth, if intrauterine transmission of SARS-CoV-2 occur. 83 There is no information found for vertical transmission of this virus from confirmed pregnant mothers to fetuses.…”