Analysis of white bile in a case of cholangiocarcinoma of the hepatic ducts

Clinical significance of white bile in the biliary tree.

“…in our series resembled that found by others (Griffiths et al, 1963;Bouchier and Cooperband, 1965). The reason why some patients with obstruction to the extrahepatic biliary tree develop white bile is unknown.…”

“…With the exception of the paper by Judd and Lyons (1923) previous reports on white bile dealt either with a single patient (Edington and McCallum, 1930;Lake, 1934;Flint, 1937;Griffiths, Haber, Rees, and Smith, 1963;Bouchier and Cooperband, 1965), or with several patients (Aronsohn, 1936;Hawthorne and Sterling, 1955), or with experiments carried oult in animals (Rous and McMaster, 1921;McMaster, Broun, and Rous, 1923;Cameron and Oakley, 1932;Aronsohn, 1935;Haber and Rees, 1963). These reports contain certain generalizations about the possible clinical significance of white bile.…”

Ileostomy and excisional surgery for chronic inflammatory disease of the colon: A survey of one hospital region: Part II The health of ileostomists

“…A total of 20 cases of the association of this tumour with ulcerative colitis has been reported up to the present time: in 17 of the cases it appears that there had been no surgical treatment for the colitis. In the three cases where such treatment had been undertaken (Rankin, Skyring, and Goulston, 1966;Griffiths, Haber, Rees, and Smith, 1963) the longest interval between the removal of the colon and the appearance of symptoms of bile-duct tumour was three years. In the present case, this interval was over 11 years.…”