1999
DOI: 10.1021/jf990444i
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Analysis of Vervain Flavonoids by HPLC/Diode Array Detector Method. Its Application to Quality Control

Abstract: A reversed-phase HPLC procedure is proposed for the determination of seven flavonoids (luteolin, nepetin, hispidulin, jaceosidin, cirsimaritin, cirsilineol, and eupatorin) in vervain samples. A simple extractive technique was developed, involving only extraction with ethyl ether, which allowed the elimination of phenolic acids, yielding a sufficiently purified flavonoid fraction. All of the analyzed vervain samples showed a common flavonoid pattern, in which hispidulin and jaceosidin were the major compounds a… Show more

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Cited by 67 publications
(42 citation statements)
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“…This chromatographic profile should be featured by the fundamental attributions of "integrity" and "fuzziness" or "sameness" and "differences" so as to chemically represent the HM investigated [11,13]. It is suggested that with the help of chromatographic fingerprints obtained, the authentication and identification of herbal medicines can be accurately conducted ("integrity") even if the amount and/or concentration of the chemically characteristic constituents are not exactly the same for different samples of this HM (hence, "fuzziness") or, the chromatographic fingerprints could demonstrate both the "sameness" and "differences" between various samples successfully [11,14]. Thus, we should globally consider multiple constituents in the HM extracts, and not individually consider only one and/or two marker components for evaluating the quality of the HM products.…”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“…This chromatographic profile should be featured by the fundamental attributions of "integrity" and "fuzziness" or "sameness" and "differences" so as to chemically represent the HM investigated [11,13]. It is suggested that with the help of chromatographic fingerprints obtained, the authentication and identification of herbal medicines can be accurately conducted ("integrity") even if the amount and/or concentration of the chemically characteristic constituents are not exactly the same for different samples of this HM (hence, "fuzziness") or, the chromatographic fingerprints could demonstrate both the "sameness" and "differences" between various samples successfully [11,14]. Thus, we should globally consider multiple constituents in the HM extracts, and not individually consider only one and/or two marker components for evaluating the quality of the HM products.…”
Section: Introductionmentioning
confidence: 99%
“…These excellent properties are the so-called dimension advantages proposed by Booksh and Kowalski [19]. A chemical fingerprint obtained by hyphenated chromatography, out of question, will become the primary tool for quality control of herbal medicines [13][14][15][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35][36][37].…”
Section: Introductionmentioning
confidence: 99%
“…In addition, these compounds are known to play an important role in maintaining fruit and vegetable quality, contributing to their organoleptic characteristics (Vaughan and Geissler, 1997 b), and have also been used for the quality control of several matrices 0308-8146/$ -see front matter Ó 2006 Elsevier Ltd. All rights reserved. doi:10.1016/j.foodchem.2006.02.013 Valentão, Andrade, Areias, Ferreres, and Seabra, 1999).…”
Section: Introductionmentioning
confidence: 99%
“…Entretanto, outras substâncias como flavonóides, iridóides e naftoquinonas também são citados com freqüência [19][20][21][22][23][24][25].…”
Section: Constituintes Químicosunclassified