Analysis of trace organic pollutants in wastewater to assess biodegradation using wrong‐way‐round ionization in liquid chromatography/tandem mass spectrometry

Su, Lijuan; Khunjar, Wendell; Aga, Diana S.

doi:10.1002/rcm.6895

Cited by 10 publications

(20 citation statements)

References 39 publications

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“…The total run time for one sample was 25 min. Electrospray ionization was achieved under positive mode for TMP and CBZ, while for SA, EE2, and NP, ionization was achieved under negative mode at a spray voltage of 4 kV situated at a 90 • angle to the entrance [37]. Drying gas temperature was set as 350 • C, nebulizer pressure (N2) as 22 psi and drying gas flow rate as 11 L/min to achieve the highest sensitivity.…”

Section: Lc-ms/ms Analysismentioning

confidence: 99%

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Factors impacting biotransformation kinetics of trace organic compounds in lab-scale activated sludge systems performing nitrification and denitrification

Aga

Chandran

et al. 2015

Journal of Hazardous Materials

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Section: Lc-ms/ms Analysismentioning

confidence: 99%

“…TOrC analyses were performed on an Agilent 1100 HPLC coupled with Agilent triple 6410 quadrupole Mass Spectrometry (Palo Alto, CA) as described elsewhere [37]. Briefly, separation was achieved on a Thermo Scientific Betabasic C18 2.1 × 100 mm, 3-m particle size column, and a guard column with the same material (Fullerton, CA).…”

Section: Lc-ms/ms Analysismentioning

confidence: 99%

Factors impacting biotransformation kinetics of trace organic compounds in lab-scale activated sludge systems performing nitrification and denitrification

Aga

Chandran

et al. 2015

Journal of Hazardous Materials

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“…conventional acidic mobile phases . The resultant improvement in signal-to-noise ratio provides lower detection limits under basic mobile-phase conditions (Su et al, 2014). The advantages of wrong-way-round ionization do not, however, extend to the analysis of macrolides, which have better ionization efficiencies under acidic conditions (Singh and Aga, 2014).…”

Section: Wrong-way-round Ionization Of Tetracycline and Sulfonamide Amentioning

confidence: 99%

Enhancing Extraction and Detection of Veterinary Antibiotics in Solid and Liquid Fractions of Manure

Wallace

Aga

2016

J. Environ. Qual.

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Analysis of veterinary antibiotics in separated liquid and solid fractions of animal manures is vital because of wide variations in the composition of agriculturally applied manure. Differentiation of antibiotic concentrations is important between liquid and solid manures, as their sorption onto the solid fraction depends on physicochemical properties of each antibiotic and manure composition (e.g., organic content, pH) and because each fraction may be treated and reused differently. Here, an efficient and sensitive method for the analysis of 22 veterinary antibiotics in the liquid and solid fractions of manure is reported. Tetracycline (TC), macrolide, and sulfonamide antibiotics were extracted from liquid manure by liquid-liquid extraction (LLE) with methanol following acidification with acetic acid. Extraction from solids was performed by sonication with acetonitrile, methanol, and 0.1 M EDTA-McIlvaine buffer. Cleanup of extracts was achieved by solid-phase extraction with hydrophilic-lipophilic balance (HLB) cartridges or tandem amino (NH2) and HLB cartridges. Quantification of antibiotics was performed by liquid chromatography-tandem mass spectrometry (LC-MS/MS) under wrong-way-round (WWR) ionization for sulfonamides and TCs and right-way-round ionization for macrolides. Recoveries of 58 to 94.7% and 62 to 94.3% were obtained in liquid and solid manure, respectively. Method detection limits range from 1.2 to 12 ng L and 0.5 to 7.9 μg kg dry wt. in liquids and solids, respectively. This method allows for extraction and analysis of both mobile antibiotics in liquid phase and hydrophobic antibiotics adsorbed on the solids. Without separate analysis, antibiotic concentrations may be improperly estimated by analyzing whole manure, as reported in many studies to date.

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“…16,22,[24][25] Fluorescence is a highly sensitive detection method, and yet it suffers from matrix interferences when it comes to complicated environmental samples. [40][41][42][43] Even though MS is a well-established detection method, it still provides room for innovation. 12,17 Hyphenated tandem mass spectrometric determination is considered as the most popular MS method for the determination of estrogens in environmental and food samples.…”

Section: Chromatographic and Hyphenated Mass Spectrometric Methodsmentioning

confidence: 99%

“… Su et al (2014) 42. analyzed trace organic pollutants including EE2 in wastewater using HLB extraction followed by HPLC-MS/MS determination.…”

mentioning

confidence: 99%

Recent advancements in analytical methods for the determination of steroidal estrogen residues in environmental and food matrices

Gunatilake¹,

Munasinghe²,

Ranaweera³

et al. 2016

Anal. Methods

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Residue steroidal estrogens in environmental and food samples have become a cause for concern as they can affect organisms at low ppt concentrations. Analytical method development plays a key role in trace estrogen analysis due to the combination of low concentrations and complicated sample matrices. Reliable quantification of these trace level steroidal estrogens has become a major concern during the past decade. This mini review focuses on advancements in analytical methods developed for estrogen detection and quantification in environmental and food samples from 2014 -2016. A comprehensive overview of the novelties and the advantages of the recently developed sample pre-concentration, clean-up, and detection methods are discussed. During the past three years, a wide variety of sample extraction methods including, the utilization of innovative imprinted magnetic sorbents, QuEChERS (Quick, Easy, Cheap, Effective, Rugged and Safe) method and various microextraction methods such as Dispersive liquid-liquid micro extraction (DLLME), Thin film micro extraction (TFME), Solid phase microextraction (SPME), and Vortex assisted hollow fiber liquid-phase micro extraction (VA-HF-LPME) have been

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Analysis of trace organic pollutants in wastewater to assess biodegradation using wrong‐way‐round ionization in liquid chromatography/tandem mass spectrometry

Cited by 10 publications

References 39 publications

Factors impacting biotransformation kinetics of trace organic compounds in lab-scale activated sludge systems performing nitrification and denitrification

Factors impacting biotransformation kinetics of trace organic compounds in lab-scale activated sludge systems performing nitrification and denitrification

Enhancing Extraction and Detection of Veterinary Antibiotics in Solid and Liquid Fractions of Manure

Recent advancements in analytical methods for the determination of steroidal estrogen residues in environmental and food matrices

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