Analysis of thyroid carcinoma based on material registered in japan during 1977-1 986 with special reference to predominance of papillary type

Ezaki, Haruo; Ebihara, Satoshi; Fujimoto, Yoshihide; Iida, Futoshi; Ito, Kunihiko; Kuma, Kanji; Lzuo, Masaru; Makiuchi, M.; Oyamada, Hiyoshimaru; Matoba, Naoya; Yagawa, Kanichi

doi:10.1002/1097-0142(19920815)70:4<808::aid-cncr2820700415>3.0.co;2-l

Cited by 72 publications

(27 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…6 The incidence of thyroid cancer is relatively high in Japan, 2 and is characterized by the predominance of papillary carcinomas. 7 However, little is known about the etiology of thyroid cancer in Japan. In a hospital-based case-control study of female thyroid cancer, an increased risk was related to history of benign thyroid diseases and high parity while a decreased risk was related to Western style breakfast and coffee consumption.…”

Section: Methodsmentioning

confidence: 99%

A Case-control Study in Hiroshima and Nagasaki Examining Non-radiation Risk Factors for Thyroid Cancer

Nagano

Mabuchi

Yoshimoto³

et al. 2007

Journal of Epidemiology

View full text Add to dashboard Cite

Section: Methodsmentioning

confidence: 99%

A Case-control Study in Hiroshima and Nagasaki Examining Non-radiation Risk Factors for Thyroid Cancer

Nagano

Mabuchi

Yoshimoto³

et al. 2007

Journal of Epidemiology

View full text Add to dashboard Cite

“…Iodinedeficient regions have a tendency to show higher rates of undifferentiated carcinomas before iodine prophylaxis as compared with post-prophylaxis periods [38,39,44,59,[65][66][67][68] and with regions with high dietary iodine intake [46,59,69]. In Salta, the decrease of undifferentiated carcinoma after iodine prophylaxis is significant and the peak age and mean age of occurrence, as in Austria for example [39], was delayed ( Table 2).…”

Section: Undifferentiated (Anaplastic) Carcinomamentioning

confidence: 99%

Thyroid Cancer, Thyroiditis and Dietary Iodine: A Review Based on the Salta, Argentina Model

Harach

Ceballos

2008

Endocr Pathol

View full text Add to dashboard Cite

Factors that should be considered when studying the effect of dietary iodine in the development of thyroid cancer include pathological criteria, diagnostic techniques, screening programs, radioactive fallout, and standard of medical care in the studied population. In most surveys, papillary carcinoma forms the largest group of thyroid malignancies, both before and after iodine prophylaxis where an increase in the papillary:follicular carcinoma ratio is also noted. Undifferentiated carcinomas decrease after salt prophylaxis. In Salta, Argentina, the increasing incidence of clinically significant papillary thyroid cancer and the decrease of undifferentiated carcinoma after iodine prophylaxis are probably due to better access to health centers and consequent earlier detection of differentiated precursor tumors. Autoimmune focal and diffuse or Hashimoto's thyroiditis are linked to dietary iodine. Pathological studies made in different regions indicate that these types of thyroiditis occur more frequently in areas of iodine sufficiency than in areas of iodine deficiency, and increase after iodine prophylaxis both in non-goitrous and iodine-deficient areas like Salta, Argentina. An increase of lymphocytic thyroiditis could be linked to an increased incidence of primary thyroid lymphoma, and thyroiditis is more commonly associated with papillary carcinoma than with other types of thyroid follicular or C-cell derived carcinomas regardless of iodine intake.

show abstract

“…Follicular carcinoma accounts for 10.9-20.5% of the patients in the United States [1,2]. In Japan, the prevalence of follicular carcinoma was reported to be 17.2% [3], but it decreased to 5% in a report by JSTS in 2004. This carcinoma is only occasionally diagnosed preoperatively, because it is hard to discriminate follicular carcinoma from benign adenoma on imaging studies and cytologic findings.…”

mentioning

confidence: 99%

Prognostic Factors and Therapeutic Strategies for Differentiated Carcinomas of the Thyroid

2009

View full text Add to dashboard Cite

Abstract. Differentiated thyroid carcinoma originates from thyroid follicular cells and is the most prominent malignancy of the endocrine organs. There are two histological types of differentiated carcinoma, namely, papillary and follicular carcinoma. According to reports from Western countries, papillary carcinoma comprises 85.3% of thyroid malignancies in whites, and 72.3% in blacks [1,2]. In Japan, a previous study showed that the prevalence of papillary carcinoma was 78.4% based on material registered between 1977 and 1986 [3], but according to recent findings reported in 2004 by Japanese Society of Thyroid Surgeons (JSTS), papillary carcinoma accounted for as much as 93% of all thyroid carcinomas. Papillary carcinoma frequently metastasizes to the regional lymph node and shows multicentricity in the thyroid gland. It usually shows a typical ultrasonographic appearance and can be rather easily diagnosed by fine needle aspiration biopsy (FNAB) [4][5][6]. Follicular carcinoma accounts for 10.9-20.5% of the patients in the United States [1,2]. In Japan, the prevalence of follicular carcinoma was reported to be 17.2% [3], but it decreased to 5% in a report by JSTS in 2004. This carcinoma is only occasionally diagnosed preoperatively, because it is hard to discriminate follicular carcinoma from benign adenoma on imaging studies and cytologic findings. In contrast to papillary carcinoma, follicular carcinoma more often metastasizes to distant organs than regional lymph nodes. In Japan, the prevalence of papillary carcinoma increased and that of follicular carcinoma decreased between reports from 1977 to 1986 and that in 2004, which may be because follicular variant of papillary carcinoma was classified into follicular carcinoma in the previous results. Generally, these carcinomas show an indolent character, but when the lesion dedifferentiates and becomes undifferentiated carcinoma, it displays very rapid growth with an adverse prognosis and is regarded even as the most aggressive malignancy among human solid carcinomas [7,8]. Furthermore, cases showing certain characteristics are likely to be constantly progressive and even become life-threatening. Such cases should be regarded as "high-risk" requiring careful and extensive surgical treatment and postoperative follow-up. Indeed, it is most important for physicians to correctly distinguish high-risk cases from those with an indolent character, although how to evaluate the biological characteristics of thyroid carcinoma and how to identify high-risk cases remains highly controversial. In this review, the methods of distinguishing high-risk cases and the appropriate therapeutic strategies for papillary and follicular carcinomas predominantly based on our experience are emphasized and our proposals for therapies including surgical treatment are demonstrated.

show abstract

Analysis of thyroid carcinoma based on material registered in japan during 1977-1 986 with special reference to predominance of papillary type

Cited by 72 publications

References 15 publications

A Case-control Study in Hiroshima and Nagasaki Examining Non-radiation Risk Factors for Thyroid Cancer

A Case-control Study in Hiroshima and Nagasaki Examining Non-radiation Risk Factors for Thyroid Cancer

Thyroid Cancer, Thyroiditis and Dietary Iodine: A Review Based on the Salta, Argentina Model

Prognostic Factors and Therapeutic Strategies for Differentiated Carcinomas of the Thyroid

Contact Info

Product

Resources

About