Analysis of the mRNA Expression Levels of Thymidylate Synthase (TS), Dihydropyrimidine Dehydrogenase (DPD) and Orotate Phosphoribosyl Transferase (OPRT) in Liver Metastases from Colorectal Cancer
Abstract:These results suggest that the mRNA expression level of TS in the liver metastases in colorectal cancer patients is a useful prognostic indicator.
“…The clinical risk score (CRS) proposed by Fong et al [4] is widely known, and it has been validated using other independent databases [8][9][10]. In Japan, the grading system developed by the Japanese Research Society for Cancer of the Colon and Rectum-the Japanese grading system (JGS) [11]-is most widely used.…”
The high predictive accuracy of both nomograms shows that these predictive tools can be used in different institutions. Patient counseling and adjuvant therapy decision-making should benefit from use of these nomograms.
“…The clinical risk score (CRS) proposed by Fong et al [4] is widely known, and it has been validated using other independent databases [8][9][10]. In Japan, the grading system developed by the Japanese Research Society for Cancer of the Colon and Rectum-the Japanese grading system (JGS) [11]-is most widely used.…”
The high predictive accuracy of both nomograms shows that these predictive tools can be used in different institutions. Patient counseling and adjuvant therapy decision-making should benefit from use of these nomograms.
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