This work presents the results of the numerical analyses pertaining to the influence of resonance vibration amplitude on the fatigue life of a compressor blade with a defect made by a collision with a hard object (FOD). The research object was the first stage compressor blade of the PZL-10W engine. The numerical simulation of the notch formation was performed for the tested blade. The material fatigue models (for e-N analysis), three cyclic hardening models, and two mean stress correction models were used in the numerical analyses. As a result of the numerical analysis, the information on the distribution of principal stress was obtained. The values of the principal stresses were used for numerical e-N fatigue analysis using the aforementioned models of fatigue, hardening, and mean stress correction. Obtained results were compared to previously published experimental research, where a notch was created at the leading edge in 8 blades. The blades damaged under laboratory conditions were subjected to experimental fatigue tests during which the effect of resonance amplitude on the number of damage cycles was determined. As a result of the comparison work carried out, the impact of the vibration amplitude on the durability of the element with plastic deformation was determined.