Analysis of the hormonal and nervous means of exerting cerebral cortical regulatory influences on the thyroid gland

Effects of fear and adrenaline on blood flow from the thyroid vein in sheep with exteriorized thyroids

“…Some apparently confficting results have arisen from this work, perhaps due to different species of animal and different intensities of stimulation. However, Amiragova (1961), using a conditioned reflex elicited by electrical stimulation of the feet of dogs, showed an increased release of thyroid 131J, both with the electrical stimulus and with the sound of a metronome evoking the reflex. With the relatively mild stimuli used in the present study, Falconer & Hetzel (1964) Figs.…”

“…Noradrenaline, depending on dose level and method of administration, may increase, decrease or have no effect on thyroid blood flow (Mowbray & Peart, 1960). Amiragova (1961) considers that adrenaline can directly influence thyroid secretion rate in the absence of the pituitary, but offers no comments on the mechanism. The influence of the adrenal medulla on thyroid secretion in the intact animal is under investigation in this laboratory at present, and may assist our understanding of the role of the thyroid in response to stress.…”

“…1, 2 and 3 and Table 1). Sympathetic nerve fibres supplying the thyroid, while having a vasomotor function, do not appear to be implicated in the reaction to pain or to reflex stimulation (Amiragova, 1961). Similarly, no difference in vasoconstriction was shown after doses of 25, 100 and 150 mg of bretylium tosylate ( Table 2).…”