Analysis of the fluid contents of simple bone cyst in the mandible

Abstract

Description of simple bone cyst (SBC) content has been controversial. This study aimed to assess and give a clearer picture of the SBC cavity contents. Between 2014 and 2016, 19 patients with SBC verified by histopathological examination were included in this study. SBC cavity content was investigated using clinical, radiographic, surgical, and laboratory findings. The difference in components among cavity fluid, blood, and serum was evaluated using a paired sample t-test for statistical analysis. All 19 SBC cases radiographically and surgically revealed a fluid-filled cavity. The patients’ average age was 21.3 ± 13.2 years, with no sex predominance found. SBCs were found mostly in the anterior mandible (n = 12, 63.2%). All lesions were filled with clear straw-colored or blood-colored floods with low concentration. Although the fluid components were similar to those in the blood and serum in the laboratory analysis, the statistical analysis revealed that the fluid components were not significantly different only for eosinophil (p = 0.43) and basophil (p = 0.06) counts as blood components and sodium (p = 0.76), potassium (p = 0.08), and chloride (p = 0.13) concentration as serum components. The results show that SBC is a fluid-filled cavity, with the cavity fluid being more likely similar to serum rather than blood regarding internal components.

Simple bone cyst recurred in adjacent areas: A case report

“… 18 A study investigating the liquid contents of simple bone cysts in the mandible confirmed that all 19 examined cysts were filled with fluid, as verified both radiographically and surgically. 17 The findings indicated that the cavities of simple bone cysts are filled with a serum-like fluid, not blood. The fluid contents of simple bone cysts may have been inaccurately characterized in previous literature, particularly if a correct aspiration procedure was not performed.…”

“…In the majority of cases, the cyst remains asymptomatic and is often detected by panoramic radiography during routine radiographic examinations. 17 Simple bone cysts are characterized by areas of well-defined unilocular radiolucency with typical scalloping borders on radiographs. 9 26 27 Another radiographic feature of simple bone cysts is the extensive spread of the lesion without causing bone expansion; the cortical bone tends to thin due to intraosseous erosion.…”

“…Radiographically, these lesions present as radiolucent, unilocular areas with scalloped margins, 6 and they rarely show expansion of the cortical bone. 7 16 For these reasons, these lesions are usually detected during radiographic exams carried out for other reasons 17 or routine radiographic examinations. 18 A radiographic assessment is useful for predicting the prognosis of simple bone cysts.…”