Analysis of the expression of PLZF and VASA genes and their protein relationships in mouse spermatogenic stem cells during the process of differentiation into sperm
M Babatabar Darzi,
F Nemati,
H Azizi
et al.
Abstract:Germ cells Spermatogonial stem cells PLZF VASAAim: Spermatogonial stem cells (SSCs) are the basis of male spermatogenesis and fertility. SSCs are distinguished by their ability to self-renew and differentiate into spermatozoa throughout the male reproductive life and pass genetic information to the next generation. Immunohistochemical analysis showed PLZF-positive cells in the basement membrane of the seminiferous tubule. It seems that the PLZF germ cell marker is specifically expressed in the spermatogonial c… Show more
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