Analysis of the Effect of Phacoemulsification and Intraocular Lens Implantation Combined With Trabeculectomy on Cataract and Its Influence on Corneal Endothelium

Wang, Bin; Tang, Liqin

doi:10.3389/fsurg.2022.841296

Cited by 3 publications

(2 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Phacoemulsi cation and trabeculectomy complement each other by reducing the role of lens abnormalities in the disease process and opening the anterior chamber angle. Intraoperative viscoelastic material increases the anterior chamber pressure and also increases the anterior chamber angle [22] . Trabeculectomy is effective in improving atrial drainage and reducing IOP [23] .…”

Section: Discussionmentioning

confidence: 99%

Effect of trabeculectomy in the treatment of primary angle-closure glaucoma combined with cataract: A case control study

Cao,

Ou,

Zhou

et al. 2023

Preprint

View full text Add to dashboard Cite

Background Elderly cataract patients usually accompany primary angle-closure glaucoma (PACG), leading to a series of pathophysiological changes in the patient’s eyes. While, the treatment of PACG combined with cataracts remains controversial. Methods A retrospective case control study was conducted. One hundred patients with PACG comorbid with cataract who were treated by phacoemulsification, intraocular lens implantation and trabeculectomy were selected as the study group. And another one hundred patients with PACG comorbid with cataract who were treated by phacoemulsification and intraocular lens implantation were selected as the control group. The intraocular pressure (IOP), best corrected visual acuity (BCVA), corneal endothelial cell density, average cell area, anterior chamber depth, anterior chamber angle width, and surgery complications before and after surgery were compared between the two groups. Results One month and three months after surgery, the IOP and BCVA of the study group were lower than those of the control group (P < 0.05). The corneal endothelial cell density of patients in the two groups at one and three months after operation was lower than that before the operation (P < 0.05), and the average cell area was larger than that before the operation (P < 0.05). There was no significant difference in the depth of the anterior chamber and the width of the anterior chamber angle between the two groups (P > 0.05). The depth and width of the anterior chamber angle in the study group were higher than those of the control at one month and three months after surgery (P < 0.05). The complication rate was lower in the study group than in the control group (P < 0.05). Conclusions Phacoemulsification, intraocular lens implantation and trabeculectomy for the treatment of PACG patients with cataract is effective and safe.

show abstract

Section: Discussionmentioning

confidence: 99%

Effect of trabeculectomy in the treatment of primary angle-closure glaucoma combined with cataract: A case control study

Cao,

Ou,

Zhou

et al. 2023

Preprint

View full text Add to dashboard Cite

show abstract

“…Endothelial cells (ECs) are critical structures within the cornea that maintain corneal clarity via their pump function. ECs are naturally lost over time but can be injured medically, surgically, or due to various dystrophies [40]. The potential risk of corneal oedema is 500-800 cells/mm 2 .…”

Section: Discussionmentioning

confidence: 99%

Efficacy and Safety of ab Externo Phaco-Canaloplasty versus First-Generation iStent Bypass Implantation Combined with Phacoemulsification in Patients with Primary Open Angle Glaucoma-Early Results

Gołaszewska

Obuchowska

Konopińska

2023

IJERPH

View full text Add to dashboard Cite

This study evaluated the early outcomes of the hypotensive efficacy and safety profile of ab externo phaco-canaloplasty versus first-generation iStent bypass implantation combined with phacoemulsification in patients with primary open-angle glaucoma (POAG). In total, 82 patients with POAG comprising 92 eyes were divided into phaco-canaloplasty (Group PC, (n = 47) or iStent combined with phacoemulsification (Group PiS, n = 45) groups. Primary outcome measures were intraocular pressure (IOP) reduction and number of glaucoma medications. Secondary outcome measures were best-corrected visual acuity (BCVA), endothelial cell density (EECD), changes in anterior chamber depth (ACD), and complication rate. The follow-up period was approximately 6 months. Preoperative IOPs were 17.30 (15.00; 19.85) mmHg and 17.50 (15.10; 20.90) mmHg in the PC and PiS groups, respectively (p = 0.876). At the end of the follow-up, IOP decreased to 15.00 (13.00; 16.00) mmHg and 15.00 (14.00; 17.00) mmHg in the PC and PiS groups, respectively (p = 0.438). Medication usage decreased from 2.08 to 0.12 and 1.40 to 0.04 in PC and PiS eyes, respectively. Most patients in both groups were medication-free at 6 months follow-up. After 6 months of observation, EECD in PC and PiS groups decreased from 2309.50 (2032.00; 2533.00) to 1966.50 (1262.00; 2353.50) and 2160.00 (1958.50; 2372.50), to1231.00 (1089.00; 2050.00), respectively (p = 0.037). Pre-surgery BCVA was 0.80 (0.50; 1.00) and 0.60 (0.40; 1.00) in PC and PiS eyes, respectively (p = 0.456). Follow-up BCVA was 0.95 (0.60; 1.00) for PC and 1.00 (1.00; 1.00) for PiS. Hyphema and corneal oedema were noted on the first day post-surgery in both groups. Subsequent complications included a transient increase in IOP in the PC group. Phaco-canaloplasty and iStent bypass implantation combined with phacoemulsification significantly lowered IOP and decreased medication burden. All eyes in both groups maintained or exhibited improved BCVA relative to baseline. Both surgeries had low postoperative complication rates and exhibited comparable safety profiles over 6-month follow-up in patients with POAG.

show abstract

Evaluating the Efficacy of Combined Surgery for Cataract and Glaucoma: A Comparative Analysis of Visual Acuity, Intraocular Pressure, and Anterior Chamber Depth

Munir,

Chaudhary,

Arshad

et al. 2024

PJHS

View full text Add to dashboard Cite

Glaucoma is characterized by an abnormal increase in intraocular pressure, leading to optic nerve damage and permanent visual impairment. Cataract is characterized by lens opacity that impairs vision but can be reversed. Objective: To compare pre and post-operative average visual acuity, intraocular pressure, anterior chamber angle, and anterior chamber depth in patients with cataract and narrow angle glaucoma undergoing combined phacoemulsification, intraocular lens implantation, and trabeculectomy. Methods: A quasi-experimental study was carried out at Niazi Welfare Foundation Teaching Hospital Sargodha from June 2022 to December 2023. Total 107 patients with both cataracts and narrow angle glaucoma were included. Post-surgery, average visual acuity, intraocular pressure, anterior chamber angle, and anterior chamber depth were assessed at various postoperative intervals (1 day, 1 week, 1 month, 3 months, and 6 months). The Patient's symptoms improved, with visual acuity and average anterior chamber depth increasing by more than 50% compared to pre-surgery was considered as significant. Data were analyzed by SPSS version 25.0. P-value <0.05 was considered as significant. Results: Results of the study yielded significant improvements in average visual acuity, intraocular pressure (IOP), anterior chamber angle, and anterior chamber depth post-operatively with complication rate of 6.52%. Conclusions: We concluded that combined phacoemulsification with intraocular lens implantation (IOL) and trabeculectomy may be an effective approach for managing intraocular pressure (IOP) and improving visual acuity in patients with narrow angle glaucoma and cataract.

show abstract

Analysis of the Effect of Phacoemulsification and Intraocular Lens Implantation Combined With Trabeculectomy on Cataract and Its Influence on Corneal Endothelium

Cited by 3 publications

References 25 publications

Effect of trabeculectomy in the treatment of primary angle-closure glaucoma combined with cataract: A case control study

Effect of trabeculectomy in the treatment of primary angle-closure glaucoma combined with cataract: A case control study

Efficacy and Safety of ab Externo Phaco-Canaloplasty versus First-Generation iStent Bypass Implantation Combined with Phacoemulsification in Patients with Primary Open Angle Glaucoma-Early Results

Evaluating the Efficacy of Combined Surgery for Cataract and Glaucoma: A Comparative Analysis of Visual Acuity, Intraocular Pressure, and Anterior Chamber Depth

Contact Info

Product

Resources

About