Abstract:Over 30% of commercial
pesticides are racemic mixtures. Nowadays,
the environmental safety of chiral pesticides has received more and
more attention. Metalaxyl is a broad-spectrum fungicide with systemic
function, which has a chiral carbon. Although its fungicidal activity
almost entirely originates from the R-enantiomer,
the enantioselective toxicity of metalaxyl in animals and human beings
are not yet clear. In this study, the urinary metabolomics approach
was applied to analyze the changes in metabolic phen… Show more
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