Analysis of the concentration of vitamin E in erythrocytes of patients with celiac disease

Romańczuk, Bartosz; Szaflarska-Popławska, Anna; Chełchowska, Magdalena; Hozyasz, Kamil K.

doi:10.5114/pg.2016.61354

Cited by 3 publications

(3 citation statements)

References 15 publications

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“…One other finding in our study was the association of CD with other autoimmune diseases such as diabetes type 1, which highlights the need for screening as well as correction of nutritional requirements for this population [ 30 , 31 ].…”

Section: Discussionmentioning

confidence: 79%

Frequency of overweight/obesity among a group of children with celiac disease in Iran

Shahraki

Hill

2018

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IntroductionA small number of overweight and obese children with celiac disease (CD) has been reported.AimTo estimate the prevalence of obesity, underweight and normal weight in a group of Iranian pediatric patients.Material and methodsIn a retrospective study from 2007 to 2015, 225 children less than 18 years old with biopsy-proven CD were enrolled. Data collected included demographic characteristics, clinical presentation, antibody titers and severity of small-bowel mucosal damage. Body mass index (BMI) profile of subjects was calculated based on the age and gender percentile at presentation.ResultsThe mean ± standard deviation (SD) for age was 7.4 ±3.8 and 62% of patients were female. Fifty-four percent of patients presented with a normal BMI, 43% were underweight, and the remaining patients (3.5%) were overweight/obese. The mean age of underweight and normal weight patients was higher than that of obese/overweight patients. Mean ± SD of TTG titer was higher in overweight/obese and normal weight children compared to underweight subjects. The majority of patients (195/225) had severe enteropathy compatible with Marsh III on duodenal biopsy. Most of the children had gastrointestinal (GI) and extra-intestinal manifestations on presentation. There was no association between severity of histological disease and BMI for age. Five out of eight cases in the obese/overweight group had an index case with CD in their family.ConclusionsThis study highlights the importance of considering celiac disease in children regardless of their BMI. Failure to diagnose CD in children leads to unnecessary diagnostic delays and long-term adverse health consequences.

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Section: Discussionmentioning

confidence: 79%

Frequency of overweight/obesity among a group of children with celiac disease in Iran

Shahraki

Hill

2018

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“…Vitamin D deficiency and resulting hypocalcaemia can lead to secondary hyperparathyroidism, which in turn stimulates bone turnover, with potential clinical consequences such as reduced bone mineral density, osteoporosis, or rickets [7,8,9]. In addition to vitamin D deficiency, other vitamin levels, including those of vitamins A and E, have been found to be decreased in CD patients [10,11]. …”

Section: Introductionmentioning

confidence: 99%

Beneficial Effect of Oligofructose-Enriched Inulin on Vitamin D and E Status in Children with Celiac Disease on a Long-Term Gluten-Free Diet: A Preliminary Randomized, Placebo-Controlled Nutritional Intervention Study

et al. 2018

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Prebiotics have been shown to improve absorption of some nutrients, including vitamins. This pilot study evaluated the effect of the prebiotic oligofructose-enriched inulin (Synergy 1) on fat-soluble vitamins status, parathormone, and calcium-related elements in pediatric celiac disease (CD) patients (n = 34) on a strict gluten-free diet (GFD). Participants were randomized into a group receiving 10 g of Synergy 1 or placebo (maltodextrin) together with a GFD. At baseline and after 3 months of intervention, 25-hydroxyvitamin D [25(OH)D], parathormone, vitamin E and A, calcium, phosphate, magnesium, total protein, and albumin were determined. Concentration of 25(OH)D increased significantly (p < 0.05) by 42% in CD patients receiving Synergy 1 in GFD, whereas no change was observed in placebo. Vitamin D status reached an optimal level in 46% of patients receiving Synergy 1. No significant difference in parathormone, calcium, and phosphate levels was observed. Concentration of vitamin E increased significantly (p < 0.05) by 19% in patients receiving Synergy 1, but not in the placebo. Vitamin A levels were not changed. Supplementation of GFD with Synergy 1 improved vitamin D and vitamin E status in children and adolescents with CD and could be considered a novel complementary method of management of fat-soluble vitamins deficiency in pediatric CD patients.

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“…The disease is characterised by abdominal pain, chronic diarrhoea, flatulence, constipation, nausea, vomiting, malnutrition, and weight loss in adults [2,4]. Other symptoms involve many systems and organs [2,[5][6][7][8]. People with diagnosed celiac disease more often suffer from comorbidities [9], including autoimmune endocrine diseases [10].…”

Section: Introductionmentioning

confidence: 99%

Quality of life of adults with celiac disease

Kamińska¹,

Wojtas²,

Kaleta³

2020

ppiel

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Introduction: Celiac disease is a food intolerance leading to problems with digestion and absorption of nutrients. It modifies the assessment of quality of life, but its overall evaluation should include sociodemographic factors and received health treatment. Aim of the study: To assess the quality of life of patients with celiac disease and to establish its determinants. Material and methods: A total of 165 adults with celiac disease participated in the study. The authors' questionnaire and the Gastrointestinal Quality of Life Index (GIQLI) questionnaire were used. Statistical analysis was performed using IBM SPSS Statistics 25, and the significance level was p < 0.05. Results: The respondents rated their quality of life in the social dimension the highest, and in the physical dimension the lowest. Age, marital status, and professional activity were not related to the overall assessment of the quality of life. This rating was higher in the group of men, residents of large cities, and people with higher education. The duration of celiac disease did not significantly affect the quality of life. Respondents without symptoms of the disease or with the occurrence of 1 or 2 of them assessed their quality of life better. Comorbidities significantly reduced quality of life. Respondents describing the support received from professionals as bad had lower quality of life in terms of physical and social functioning. Conclusions: Treatment of celiac patients requires professionals providing care to implement interventions in order to improve patients' assessment of quality of life.

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Analysis of the concentration of vitamin E in erythrocytes of patients with celiac disease

Cited by 3 publications

References 15 publications

Frequency of overweight/obesity among a group of children with celiac disease in Iran

Frequency of overweight/obesity among a group of children with celiac disease in Iran

Beneficial Effect of Oligofructose-Enriched Inulin on Vitamin D and E Status in Children with Celiac Disease on a Long-Term Gluten-Free Diet: A Preliminary Randomized, Placebo-Controlled Nutritional Intervention Study

Quality of life of adults with celiac disease

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