Analysis of the characteristics of Global synthetic biology research and reference to technical layout

Abstract

Background. In order to understand the research status and hotspots in the field of global synthetic biology, this paper analyzes the gaps and differences between China's synthetic biology research and foreign counterparts. Methods. Using the scientmetric tool CiteSpace, 12040 academic papers with the theme of synthetic biology, which were included in the Web of Science core set database in the past 15 years from 2008 to 2023, were visually analyzed. Results. The study found that: at the country level, the United States continues to lead the research in the field of global synthetic biology, and had obvious advantages and dominant positions. Through the bibliometric analysis of the literature, we found that, Synthetic biologye research focused mostly on the keywords "genome", "models", "proteins", "complex", "cells", and "gene cluster". The fragmentation of China's synthetic biology research network is prominent. Conclusions. On the whole, if China can fully absorband learn from the strategically oriented scientific and technological management experience in the field of synthetic biology from major competing countries such as the United States, give full play to the advantages of the national system, transform and utilize the existing achievements, and at the same time attach importance to emphasis on basic R&D investment and talent base training, expanding orderly participation, will have the opportunity to become a high ground for global synthetic biology and innovation practice in the technology industry in the future.