Analysis of temporal artery biopsies in an 18-year period at a community hospital

Marí, Begoña; Monteagudo, Manuel; Bustamante, Edna Gómez; Pérez, Javiera; Casanovas, A.; Jordana, R.; Tolosa, Carlos; Oristrell, J

doi:10.1016/j.ejim.2009.05.002

Cited by 43 publications

(35 citation statements)

References 19 publications

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“…In the study of Hayreh et al, neck pain, an elevated ESR, an elevated CRP, and an age above 75 were predictors of a positive test result [14]. Regarding the fact that the temporal artery is not always involved in GCA, these symptoms and abnormalities do not necessarily have to be predictive of a positive test result of the 18 F-FDG PET(/CT) scan [9][10][11][12][13][14]38]. This is reflected by the low number of reported symptoms of temporal arteritis in our study.…”

Section: Discussionmentioning

confidence: 92%

“…A few studies have been published with a similar goal concerning biopsies of the temporal artery for diagnosing GCA. Mari et al found headache, jaw claudication, and palpable abnormalities of the temporal artery as predictors of a positive test result, whereas anemia appeared to be a predictor of a negative test result [11]. In the study of Hayreh et al, neck pain, an elevated ESR, an elevated CRP, and an age above 75 were predictors of a positive test result [14].…”

Section: Discussionmentioning

confidence: 95%

“…Temporal artery biopsy is considered the cornerstone of the diagnosis of GCA; however, it is invasive and can be false negative in 15-70% of the cases, which may delay the diagnosis [9][10][11][12][13][14]38]. This could explain why visual loss in one eye was reported to be prevalent in only 16-18% of patients at initial diagnosis [39,40].…”

Section: Discussionmentioning

confidence: 97%

“…The diagnostic reference method for GCA is a temporal artery biopsy, but the test results can be false negative. A falsenegative rate of 15-70% is reported; therefore, the incidence of GCA might be underestimated [9][10][11][12][13][14].…”

Section: Introductionmentioning

confidence: 99%

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Parameters related to a positive test result for FDG PET(/CT) for large vessel vasculitis: a multicenter retrospective study

et al. 2012

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The purpose of this study was to identify clinical and laboratory parameters that may improve the effectiveness of the use of fluorodeoxyglucose positron emission tomography ((18)F-FDG PET)(/CT) for diagnosing large vessel vasculitis (LVV), and secondarily to assess the contribution of (18)F-FDG PET/CT in finding other diagnoses for patients without signs of LVV on the scan. A multicenter retrospective study of (18)F-FDG PET(/CT) scans performed between January 2000 and December 2009 for clinical suspicion of LVV was conducted. A total of 304 (18)F-FDG PET(/CT) scans were included, of which 62 (20%) were positive and 242 (80%) were negative for LVV. Univariate analysis showed that patients with a positive scan were older (65.9 ± 13.4 versus 58.6 ± 16.5 years, p = 0.002), were more frequently female (76% versus 55%, p = 0.002), more often had a history of temporal arteritis (10% versus 3%, p = 0.044), less frequently had artralgia (31% versus 67%, p = 0.000), and had higher thrombocyte counts (434 ± 161 versus 373 ± 168 × 10(9)/l, p = 0.049) and a higher erythrocyte sedimentation rate (ESR) (72.6 ± 31.0 versus 51.4 ± 30.5 mm/h, p = 0.001) than patients with a negative scan. In the multivariate analysis, only artralgia (OR 0.091; 95% CI 0.023-0.366) and ESR (OR 1.024; 95% CI 1.002-1.046) remained statistically significant predictors. The presence of artralgia is a statistically significant negative predictor and an elevated ESR a statistically significant positive predictor of LVV showing up on (18)F-FDG PET(/CT). A reliable prediction of the outcome of the scan, based on these two parameters, is not possible however. (18)F-FDG PET(/CT) allows early diagnosis of LVV and may discover occult inflammatory or neoplastic disorders.

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Section: Discussionmentioning

confidence: 92%

Section: Discussionmentioning

confidence: 95%

Section: Discussionmentioning

confidence: 97%

Section: Introductionmentioning

confidence: 99%

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Parameters related to a positive test result for FDG PET(/CT) for large vessel vasculitis: a multicenter retrospective study

et al. 2012

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“…Of major concern is the low number of positive biopsies analyzed by pathological departments. Studies during the years 1976 to 2007 have reported findings of GCA in 13 -43.7 % of TABs (19,226,233,234,235). Consequently, predictive markers for a positive biopsy have long been searched for.…”

Section: Temporal Artery Biopsymentioning

confidence: 99%

Diagnosis and Treatment of Giant Cell Arteritis (Temporal Arteritis) – Past, Current and Future Aspects

Gran¹

2011

Advances in the Diagnosis and Treatment of Vasculitis

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Diagnostic Accuracy of Symptoms, Physical Signs, and Laboratory Tests for Giant Cell Arteritis

et al. 2020

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Analysis of temporal artery biopsies in an 18-year period at a community hospital

Cited by 43 publications

References 19 publications

Parameters related to a positive test result for FDG PET(/CT) for large vessel vasculitis: a multicenter retrospective study

Parameters related to a positive test result for FDG PET(/CT) for large vessel vasculitis: a multicenter retrospective study

Diagnosis and Treatment of Giant Cell Arteritis (Temporal Arteritis) – Past, Current and Future Aspects

Diagnostic Accuracy of Symptoms, Physical Signs, and Laboratory Tests for Giant Cell Arteritis

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