Analysis of Synovial Fluid for Study of Diseases of Joints Using the Method of Raman Spectroscopy

Abstract

This paper presents the results of experimental studies using the synovial fluid Raman spectroscopy method, which was obtained from the joint cavity during the operation. By analyzing the composition of the synovial fluid, it was found that with the development of the degenerative-dystrophic process in the synovial fluid of the affected joint, the total number of components at wave numbers: 1155 cm-1 (Hyaluronic acid (C-O, C-C)) and 1250 cm-1 (Amide III). The introduced optical coefficients allow estimating the synovial fluid in osteoarthritis and further this method of Raman spectroscopy can become a new diagnostic screening for the detection of articular pathology.