Analysis of solutions containing glutathione and inorganic nitrite: Application to nitroglycerin metabolism studies

Curry, Stephen H.; Aburawi, Suher M.; Whelpton, Robin

doi:10.1016/0731-7085(87)80031-6

Journal of Pharmaceutical and Biomedical Analysis

1987

DOI: 10.1016/0731-7085(87)80031-6

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Analysis of solutions containing glutathione and inorganic nitrite: Application to nitroglycerin metabolism studies

Stephen H. Curry

Suher M. Aburawi

Robin Whelpton

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2012

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“…Gerarde stated that all aconite species are 'deadly to man, likewise to all other living creatures" (9,18). However, even, this very deadly herb did have medicinal uses for treatment of fever and pain when applied externally, so it would make sense than an apothecary might carry it (10,20). We revealed that the effects of Aconitum napellus have also been referred to by Shakespeare in Henry IV, "King Henry …though it do work as strong/As aconitum…" (2 Henry IV, 4.4.49-50).…”

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confidence: 99%

O True Apothecary: How Forensic Science Helps Solve a Classic Crime

Harper-Leatherman

Miecznikowski

2012

J. Chem. Educ.

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As part of a university-wide project to explore Shakespeare's classic play, Romeo and Juliet, from a variety of perspectives, we presented an interdisciplinary talk to our university community on the chemistry of the potions and poisons referenced in Romeo and Juliet. To draw our multidisciplinary audience in and to teach about forensics as well as pharmaceutical herbs and chemicals, our presentation was given from the perspective of how a modern crime scene investigator would approach the famous play's final death scene without any prior knowledge of the situation. We described how if an autopsy of Juliet's body had been done, it might have revealed the presence of the chemicals, hyoscine and atropine, that come from the plant, Atropa belladonna. The autopsy could reveal whether or not the Friar had truly set out to sedate Juliet, or if he had attempted to kill her. An autopsy of Romeo's body might have revealed the presence of aconitine from the plant, Aconitum napellus. Through this approach of using a classic story to teach about chemistry, we were able to introduce basic ideas about forensics and pharmacology, emphasizing the importance of dose when determining the effect of a drug on the human body.

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confidence: 99%

O True Apothecary: How Forensic Science Helps Solve a Classic Crime

Harper-Leatherman

Miecznikowski

2012

J. Chem. Educ.

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Analysis of solutions containing glutathione and inorganic nitrite: Application to nitroglycerin metabolism studies

Cited by 1 publication

References 10 publications

O True Apothecary: How Forensic Science Helps Solve a Classic Crime

O True Apothecary: How Forensic Science Helps Solve a Classic Crime

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