“…The literature contains no other data regarding the association of TNF-a (-308) polymorphism and chronic periodontitis in a Turkish population. Majority of the studies in parallel to ours, revealed no significant difference between chronic periodontitis and healthy [17,[19][20][21]23,31,[33][34][35]. Kornmann et al [16], reported the frequency of TNF-a (-308) allele 2 20.9%, 38.1%, and 26.5% for severe, moderate and mild periodontitis respectively.…”