Analysis of selected factors influencing seroma formation in breast cancer patients undergoing mastectomy

Zieliński, Jacek; Jaworski, Radosław; Irga, Ninela; Kruszewski, Janusz; Jaśkiewicz, Janusz

doi:10.5114/aoms.2012.29219

Cited by 52 publications

(51 citation statements)

References 32 publications

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“…Similar conclusions were drawn by Sforza et al (39). Other studies have shown a correlation (1,20). According to our analyses, comorbidities such as diabetes mellitus or arterial hypertension appear to be unrelated to an increased rate of postoperative seroma formation.…”

Section: Discussionsupporting

confidence: 92%

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The Use of TissuGlu® Surgical Adhesive for Mastectomy with or Without Lymphonodectomy

Öhlinger

Gieron

Rutkowski

et al. 2018

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Section: Discussionsupporting

confidence: 92%

“…This seems to be due to the direct causality between resected volume and dead space. Similar findings were obtained by Zielinski et al in a prospective study (20). Baker et al could not establish a correlation between weight of the resected tissue and seroma formation (9).…”

Section: Discussionsupporting

confidence: 70%

The Use of TissuGlu® Surgical Adhesive for Mastectomy with or Without Lymphonodectomy

Öhlinger

Gieron

Rutkowski

et al. 2018

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“…Similar observation was reported by another study form Poland. 18 Tumour size had a directly proportional relationship to the incidence of seroma formation in our study. Nodal metastasis was associated with higher incidence of seroma formation 38.46% compared to 28.57% when there was no metastasis.…”

Section: Discussionsupporting

confidence: 57%

Factors Predicting Seroma Formation after Axillary Lymph Node Clearance

Goud¹,

Ali²,

Sivender³

2019

jebmh

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BACKGROUND We wanted to investigate as to which variable like age, weight, stage, prior chemotherapy, radiation therapy etc. had a significant association with the patient developing collection of serous fluid in the axilla in the post-operative period following axillary lymph node clearance. METHODS This is a retrospective study. All patients who underwent axillary clearance were included in the study including elective and therapeutic indications. All relevant clinical data was extracted from these patients. The clinical variables were studied to reveal the most significant variable associated with formation of seroma RESULTS Axillary dissection was carried out in 133 patients, 70 patients as a part of modified radical mastectomy for carcinoma breast, 39 patients as a part of breast conserving surgery for carcinoma breast, 12 patient as a part of completion surgery for patients who underwent mastectomy elsewhere for carcinoma breast in which axilla was not addressed, 6 patient with melanoma of the upper limb and 4 for squamous cell carcinoma of upper limb and 2 for sarcoma for the upper limb. Incidence of seroma was 43.47 in >60 yrs. vs 31.04 in <60 yrs., 80% in males vs 33.60% in females, 29.14% for tumour size of 2 cm vs 37.25% for 2-5 cm, vs 41.97% for > 5 cms, 38.46% nodal metastasis vs 28.57 no nodal metastasis, 34.28% in MRM vs 23.07% in BCS vs 41.66% in Completion Mastectomy, neoadjuvant chemotherapy had 54.84% vs 29.41% in no prior chemotherapy, infection/flap necrosis 83.33% vs 30.58 in no infection/ flap necrosis, 85.71% when drainage duration 5 days vs 75% when 5 to 10 days vs 20.40% when more than 10 days. Melanoma and sarcoma histology had higher incidence of seroma formation. CONCLUSIONS Male sex, older age, larger tumour size, nodal involvement, completion surgery or re-surgery, histology like melanoma or sarcoma, neoadjuvant chemotherapy, prior irradiation, infection or flap necrosis, and early removal of drain is associated with higher incidence of post-operative seroma formation.

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“…26,27 The etiology is multifactorial involving the lymphatic and vascular channels disruption, concurrent nodal dissection, shearing effects of the subcutaneous tissue on the underlying muscle, dead space, and mediators of inflammation and infection. 28 LD flap was harvested without additional subcutaneous tissue. The Scarpa's fascia was left intact to the margin of the donor area defect to preserve the blood supply offering excellent strong tissues for tension-free donor-site closure.…”

Section: Discussionmentioning

confidence: 99%

Tips and Tricks to Improve Clinical and Aesthetic Outcomes in Latissimus Dorsi Flap Breast Reconstruction

Laporta

Sorotos

Longo

et al. 2017

J reconstr Microsurg

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The aim of this study is to present technical strategies to decrease donor-site complications, to optimize breast shaping, and to achieve symmetry in one-stage procedure in latissimus dorsi (LD) flap reconstruction. Between 2004 and 2014, a retrospective review was performed on LD flap reconstructions. Demographics, reconstructive details, clinical and aesthetic outcomes were collected and analyzed. Patients were divided in historical control group (HCG) and new strategy group (NSG). In HCG, a horizontal/oblique LD skin paddle (SP) was drawn; only LD muscle was harvested for the implant pocket; and a contralateral symmetrization was planned without any algorithm. In NSG, a transverse LD-SP was centered on the middle to lower bra strap area; a double-layer muscle coverage was used to create the implant pocket; and a planning algorithm was developed to achieve symmetry. A total of 418 breast reconstructions were performed on 296 patients. The two groups were homogeneous regarding demographics, mastectomy weight, and implant volume ( > 0.05). No differences were observed in the incidence of a contralateral surgery, mean hospitalization time, and mastectomy skin flap and nipple-areola complex complications ( > 0.05), while surgical revision of the balancing procedure was more common in HCG than NSG ( = 0.001). Overall, donor-site morbidities occurred in 50 cases including 3 (1%) seroma in NSG and 17 (14.1%) in HCG, and 8 (2.7%) wound dehiscence in NSG and 18 (14.5%) in HCG ( = 0.001). Mean number of take backs to the operating room for secondary procedure was statistically significant between the groups in favor of NSG ( = 0.001). Careful preoperative planning and adoption of appropriate reconstructive strategies can improve clinical and aesthetic outcomes in LD flap breast reconstruction at long-term follow-up. This is a level III, therapeutic study.

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Analysis of selected factors influencing seroma formation in breast cancer patients undergoing mastectomy

Cited by 52 publications

References 32 publications

The Use of TissuGlu® Surgical Adhesive for Mastectomy with or Without Lymphonodectomy

The Use of TissuGlu® Surgical Adhesive for Mastectomy with or Without Lymphonodectomy

Factors Predicting Seroma Formation after Axillary Lymph Node Clearance

Tips and Tricks to Improve Clinical and Aesthetic Outcomes in Latissimus Dorsi Flap Breast Reconstruction

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