Analysis of Salivary Proteome in Patients with Dental Caries employing Electrophoresis and Mass Spectrometry

Vibhakar, Pavitra Ajit; Patankar, Sangeeta; Vibhakar, Parag A; Kumar, Amit

doi:10.5005/jp-journals-10052-0107

Cited by 3 publications

(5 citation statements)

References 13 publications

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“…In the current study, there were no statistically significant changes in total protein levels based on age. This finding differs from that of Vibhakar et al (16) , which could be due to the small age group in the current investigation.…”

Section: Discussioncontrasting

confidence: 99%

“…This finding …. Salivary antioxidents in relation to caries severity MDJ 316 among young people coincides with certain studies (16,18) but contradicts with others (14,17) . In the current investigation, the mean of salivary superoxide dismutase was found to be greater in the group with caries-free than in the group with caries-active, which contradicts the findings of Hedge et al (19) .…”

Section: Discussionmentioning

confidence: 61%

“…The current study discovered that the protein profile in females was more concentrated than that in males, taking total protein levels in saliva and gender into account, which is consistent with research done among young adults (14,17) . Another study (18) was conducted among dentistry students, and it differ levels in saliva from Vibhakar et al (16) in that they did not provide an explanation, and this point of contention requires additional inquiry.…”

Section: Discussionmentioning

confidence: 96%

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Salivary antioxidents in relation to caries severity among a group of young adults

Faris Abdel Aziz,

Ali Jasim

2023

MDJ

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Background: Saliva represents the body's stages of toxicological, hormonal, immunological, and markers of many infectious disease and disorders, so that it's an ideal tool for monitoring oral and systemic health. Antioxidants help the body's defensive system by reducing oxidative stress. Aims of the study: The study was directed to estimate the carious lesion experience (DMFS) in relation to salivary superoxide dismutase and total protein among adults by age and gender. Materials and methods: Caries experiences was assessed according to DMFS index, after investigation eighty peoples of an age 19-22 years for both genders. Stimulated salivary samples were together and chemically assessed to detect selected salivary antioxidants (superoxide dismutase, total protein), under standardized condition. Total protein and superoxide dismutase were measured by spectrophotometric examination. Results: With not-significant differences, total protein was found to be higher in the caries active group than in the caries free group, but salivary superoxide dismutase was the opposite. with statistically not-significant differences, females had a greater average of the salivary total protein than men, whereas men had a greater average of salivary superoxide dismutase than females. the first group (19-20 years) had a not-significant greater average salivary total protein and salivary superoxide dismutase than the second group (21-22 years). Conclusion: Salivary superoxide dismutase is the important factor in dental caries prevention. As a result, alterations in salivary content are crucial in the development and progression of dental caries.

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Section: Discussioncontrasting

confidence: 99%

Section: Discussionmentioning

confidence: 61%

Section: Discussionmentioning

confidence: 96%

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Salivary antioxidents in relation to caries severity among a group of young adults

Faris Abdel Aziz,

Ali Jasim

2023

MDJ

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“…A study reported that in diabetes, dental caries prevalence was high but other study reported that there was no such difference. Therefore the statement regarding this was contradictory (12) . Due to damage to microvasculature basement membranes of salivary glands changes resulting in increase glucose leakage from cells of ducts resulting in increase glucose level in saliva and crevicular space.…”

Section: Resultsmentioning

confidence: 99%

Diabetes and Dental Caries in Relation to Oral Health – An Empirical Review

Ambikathanaya¹,

Swamy²,

Gujjari³

et al. 2023

IJST

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Objective: This review was undertaken to determine whether diabetes and it's associated factors has an impact on prevalence of dental caries. Methods: The review considered the articles included in Pubmed, Scopus, Cochrane, Google scholar & Web of Science from 2011 to 2022 that focused on diabetes and dental caries. Articles covered in editorials and abstracts were excluded. The articles were searched using the keywords: diabetes, dental caries & oral hygiene. The data required for the review was extracted from section such as result, discussion and conclusion. Findings: The review states that good metabolic control & oral hygiene in diabetic patients plays a vital role in prevalence of dental caries. Other factors such as physical disabilities, inactivity, low socioeconomic status, lack of oral health education, stress, psychological problems also contributes to the quality of oral health. Novelty: This review evaluates the association of other additional contributing factors such as stress, obesity, physical disabilities, psychological problems affecting the oral health. This review discussed more about additional contributing factors. Conclusion:The review gives the advance outcome of present diabetic patients' condition. Apart from good metabolic control and good oral hygiene, stress, depression, psychological problems commonly found in diabetic patients affects the oral health.

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“…Exclusion criteria involved oral infections, ulcers, extensive periodontal diseases except for caries, smoking, pregnancy, and the use of chronic diseases medications. 16,17 Three groups were organized, relying on the DMFT index as a diagnostic criterion; caries free (CF); DMFT = zero, very low caries (VL); DMFT 1-4, and lowto-moderate caries (LM) DMFT ≤ 5…”

Section: Methodsmentioning

confidence: 99%

Experimental studies on the pH levels that affect demineralization and remineralization of human tooth enamel

Muhammad¹

2022

EDJ

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Experimental studies on the pH levels that affect demineralization and remineralization of human tooth enamel tometer. A correlation test and regression plot were used for the data analysis. Results: Significant correlations were obtained between the pH levels (4.6 to 7.0) and the demineralization/remineralization of enamel. Moreover, regression plots between the pH and calcium concentrations resulted in new pH points that may play effective roles in the demineralization and remineralization processes. Conclusion: New pH levels have been obtained regarding demineralization and remineralization of enamel. Responses to fluctuations in these pH levels differ from person to person, which in turn lead to a variation in the incidence and severity of tooth decay.

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Analysis of Salivary Proteome in Patients with Dental Caries employing Electrophoresis and Mass Spectrometry

Cited by 3 publications

References 13 publications

Salivary antioxidents in relation to caries severity among a group of young adults

Salivary antioxidents in relation to caries severity among a group of young adults

Diabetes and Dental Caries in Relation to Oral Health – An Empirical Review

Experimental studies on the pH levels that affect demineralization and remineralization of human tooth enamel

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