Analysis of risk factors for the early death of lymphocyte subsets in adult patients with secondary hemophagocytic lymphohistiocytosis
Xiaosui Ling,
Heng Chen,
tangxing Xu
et al.
Abstract:Background
Hemophagocytic lymphohistiocytosis (HLH) is an excess inflammatory response syndrome caused by genetic or acquired immune dysregulation.
Method
We examined the expression levels of lymphocyte subsets in the peripheral blood of 96 patients with sHLH.
Result
This study found that CD3-CD16 + CD56 + cells < 2% and CD3 + cells < 50% were important risk factors for early mortality in sHLH patients. Furthermore, age ≥ 55 years and Hemoglobin(HGB)< 70g/L were also found to be risk factors for ea… Show more
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