Analysis of Risk Factors for Low Bone Mineral Density in Patients with Inflammatory Bowel Disease

Abstract

Low BMD is a common feature in Korean IBD patients, even those who do not use glucocorticoid. The multiple factors may be involved in the pathogenesis of low BMD. Therefore, BMD should be examined in all IBD patients, irrespective of glucocorticoid treatment.

Nutrient Intake and Bone Mineral Density by Nutritional Status in Patients with Inflammatory Bowel Disease

“…In the present study, the decrease in bone density was greater in the malnourished group than in the normal group as determined by the World Health Organization osteoporosis criteria, but the difference was not significant. Further, the decrease in bone density of 41.5% reported in the Korean IBD patients in our study was lower than the 63.3% cited by Park et al[20] It was difficult to accurately compare between our study and the study by Park et al[20] because of the different set of subjects and disease period. Nonetheless, both studies showed that bone density testing and active management from the early stages of diagnosis are necessary to prevent long-term complications of IBD.…”

“…[20,27,28] However, more recommendations indicate that daily management is required to ensure adequate levels of calcium and vitamin D in the diet and to improve malnutrition to prevent osteoporosis. [1,29] Because of the limited number of subjects, this study was not able to represent all IBDs.…”

Can Early Onset of Disease Be One of the Risk Factors for Low Bone Mineral Density in Patients with Inflammatory Bowel Disease?

“…However, Kim et al9 failed to confirm a significant difference in BMI between IBD patients with a normal BMD and those with a low BMD (21.8±3.1 vs. 21.8±4.8, p =0.97) even as a known a risk factor for low BMD. This result coincides with that of the study reported by Park et al10…”