Analysis of Risk Factors Affecting the Outcome of Critically Ill Pregnant and Postpartum Women

Abstract

The mortality of critically ill pregnant women is an important global health concern. Therefore, we evaluated the risk factors affecting the mortality of critically ill pregnant women admitted to the intensive care unit. All critically ill pregnant patients >18 year from the second affiliated hospital of Wenzhou Medical University. Finally, a total of 100 adult pregnant women were admitted to the intensive care unit. 69 pregnant women were survivor (28.29 ± 4.70 year) with gestational age of 33.33 ± 6.13 week; while 31 pregnant women non-survivor (29.50 ± 5.37 year) with gestational age of 33.21 ± 3.44 week. Multivariable logistic regression analysis showed that PT(OR:6.409; 95% CI, 1.855-22.140; p=0.003), total bilirubin (OR:3.125; 95% CI, 1.013-9.644; p=0.037) and APACHE III score (OR:4.750; 95% CI, 1.488-15.167; p=0.009) were associated with maternal mortality. Considering these promising results, PT, total bilirubin and APACHE III score significantly affect the outcomes of pregnant women admitted to the ICU. Critically ill pregnant patients with liver problems should be carefully monitored.