Analysis of Remineralization Potential of Three Different Remineralizing Pastes on Demineralized Enamel: A Comparative Study

Dixit, Arti; Mampilly, Mathew O; Nallamothu, Raghuveer; Gopakumar, R; Jayachandran, Mahesh; Terence, Nithu M

doi:10.5005/jp-journals-10024-3095

Cited by 3 publications

(1 citation statement)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Hydroxyapatite crystals, which are calcium phosphate salts, make up the mineral composition of enamel [1], resulting in enamel prisms [2]. Dixit et al, in 2021 stated that dental caries results in focal disintegration of the mineralised tissues of teeth which is attributed to numerous cycles of demineralisation and remineralisation, with the intervening phases being either reversible or irreversible [3].…”

Section: Introductionmentioning

confidence: 99%

Effectiveness of Self-Assembling Peptide (P11-4) in Dental Hard Tissue Conditions: A Comprehensive Review

et al. 2022

View full text Add to dashboard Cite

The limitations on the use of fluoride therapy in dental caries prevention has necessitated the development of newer preventive agents. This review focusses on the recent and significant studies on P11-4 peptide with an emphasis on different applications in dental hard tissue conditions. The self-assembling peptide P11-4 diffuses into the subsurface lesion assembles into aggregates throughout the lesion, supporting the nucleation of de novo hydroxyapatite nanocrystals, resulting in increased mineral density. P11-4 treated teeth shows more remarkable changes in the lesion area between the first and second weeks. The biomimetic remineralisation facilitated in conjunction with fluoride application is an effective and non-invasive treatment for early carious lesions. Despite, some studies have reported that the P11-4 group had the least amount of remineralised enamel microhardness and a significantly lower mean calcium/phosphate weight percentage ratio than the others. In addition, when compared to a low-viscosity resin, self-assembling peptides could neither inhibit nor mask the lesions significantly. Moreover, when it is combined with other agents, better results can be achieved, allowing more effective biomimetic remineralisation. Other applications discussed include treatment of dental erosion, tooth whitening and dentinal caries. However, the evidence on its true clinical potential in varied dental diseases still remains under-explored, which calls for future cohort studies on its in vivo efficacy.

show abstract

Section: Introductionmentioning

confidence: 99%

Effectiveness of Self-Assembling Peptide (P11-4) in Dental Hard Tissue Conditions: A Comprehensive Review

et al. 2022

View full text Add to dashboard Cite

show abstract

Remineralizing potential of Calcium Sucrose Phosphate in white spot lesions: A Systematic Review

Rout,

Patil,

Deshmukh

et al. 2024

Journal of Oral Biosciences

View full text Add to dashboard Cite

Role of calcium sucrose phosphate (CaSP) in dental carries

Trailokya,

Amar Shirsat

2024

JOHS

View full text Add to dashboard Cite

Oral health is an essential component of overall well-being is often neglected across world and specially in India. Dental caries, or tooth decay, represents one of the most significant and prevalent problems in oral health. Demineralization is a harmful process in which essential mineral ions are removed from the hydroxyapatite crystals that make up dental enamel, which can result in tooth decay. On the other hand, remineralization is the process of strengthening enamel by replacing lost mineral ions. This process is essential for reversing early signs of dental caries. Calcium Sucrose Phosphate (CaSP), a chemical that has been emphasized for its effectiveness as a demineralizing agent. Calcium Sucrose Phosphate 's mode of action directly enhances the remineralization process by increasing the concentration of calcium and phosphate ions in saliva, strengthening dental enamel, and preventing decay.

show abstract

Analysis of Remineralization Potential of Three Different Remineralizing Pastes on Demineralized Enamel: A Comparative Study

Cited by 3 publications

References 13 publications

Effectiveness of Self-Assembling Peptide (P11-4) in Dental Hard Tissue Conditions: A Comprehensive Review

Effectiveness of Self-Assembling Peptide (P11-4) in Dental Hard Tissue Conditions: A Comprehensive Review

Remineralizing potential of Calcium Sucrose Phosphate in white spot lesions: A Systematic Review

Role of calcium sucrose phosphate (CaSP) in dental carries

Contact Info

Product

Resources

About