Analysis of purity and cutting agents in street mephedrone samples from South Wales

4F-PBP (4′-fluoro-α-pyrrolidinobutyrophenone), a new substance of abuse: Structural characterization and purity NMR profiling

“…Indeed, it is documented that 'bath salts' and powders, tablets or capsules containing cathinones consist typically of one or several synthetic cathinones, often mixed with other substances such as caffeine, topical anesthetics, binding and cutting agents, and even other illicit drugs [28]. For instance, a study of street mephedrone seized in South Wales over two years Page 19 of 22 A c c e p t e d M a n u s c r i p t 19 showed a decrease in sample's purity after the UK ban, with the most common cutting agents being sodium monoglutamate, sucrose and creatine [29]. Benzocaine was also reported as a cutting agent for the synthetic cathinone flephedrone [22].…”

Identification and quantification of metabolites of AB-CHMINACA in a urine specimen of an abuser

“…In recent years, various types of synthetic cannabinoids [1][2][3][4] and cathinone derivatives [5][6][7][8] have become widely distributed, and are now causing social problems throughout many parts of the world. The newly emerging drugs seem to have become more potent than the previous ones, and sometimes cause deaths [9][10][11][12][13][14][15].…”

Assessing the ‘added value’ of European policy on new psychoactive substances

“…Furthermore, the EMCDDA (2011a, p. 3) reports that "control of GHB ... may have led to a rise in the use of its chemical and metabolic precursor GBL..., which is at least as dangerous as GHB". Others have reported that stricter control can also result in a decrease in purity of substances available (Miserez, Ayrton & Ramsey, 2014) and an increase in price (Wood et al, 2012).…”