2022
DOI: 10.4018/ijssci.312562
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Analysis of Protein Structure for Drug Repurposing Using Computational Intelligence and ML Algorithm

Abstract: Proteins are fundamental compounds in biological processes during the analysis of drug target indication for drug repurposing. The identification of relevant features is a necessary step in determining protein structure. A classification technique is used to identify the most important features in a dataset, which is why feature selection is so important. For protein structure prediction, recent research has developed a wide range of new methods to improve accuracy. The authors use principal component analysis… Show more

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Cited by 8 publications
(1 citation statement)
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“…To enhance mapping ability, customized kernels (kernels fulfilling Mercer's Theorem) can be designed for desired applications [51]. The advantages of SVMs are the flexibility of kernel tricks to separate between classes, higher memory efficiency to work in high-dimensional feature spaces, and fewer convex optimization problems [52].…”
mentioning
confidence: 99%
“…To enhance mapping ability, customized kernels (kernels fulfilling Mercer's Theorem) can be designed for desired applications [51]. The advantages of SVMs are the flexibility of kernel tricks to separate between classes, higher memory efficiency to work in high-dimensional feature spaces, and fewer convex optimization problems [52].…”
mentioning
confidence: 99%