Analysis of prescription pattern in patients on maintenance hemodialysis

Abstract

Background: Chronic kidney disease (CKD) is a world-wide public health problem associated with various complications. CKD patients undergoing hemodialysis have associated comorbidities and prescribing drugs rationally in these patients is a difficult task. Objective: To evaluate the prescribing patterns of medicines in CKD patients on maintenance hemodialysis. Methodology: A Cross-sectional, hospital-based observational study was conducted in King Khalid General Hospital, Al Majmaah for a period of one year. The records of patients in the given period were examined and data pertaining to prescriptions was analyzed. Results: A total of 41 prescriptions of patients were analyzed. The most common associated co-morbidity was hypertension in 82.9% of the patients, followed by anemia in 73.1% of patients and secondary hyperparathyroidism in 63.4% of the patients. 85.4% of the patients had more than one comorbidity. The total number of drugs prescribed was 504 and the average number of prescriptions per patient was 12.3. The percentage of drugs prescribed using generic name was 71.4 and 65.3% drugs prescribed were from the WHO essential drugs list. Total number of Fixed dose combinations used was only 1.2%. Conclusion:The study has generated a profile of drugs prescribed in CKD patients on maintenance hemodialysis in a secondary care hospital in Saudi Arabia. High number of medications were used per prescription in this study thus increasing the possibility of drug interactions and Adverse events. Further studies with special consideration for drug-drug interactions, adverse events and adherence need to be conducted.

Assessment of Prescribing Patterns of Drugs in Chronic Kidney Disease Patients in a Tertiary Care Hospital

“…In this study the males were in the majority compared to female subjects which coincides with the study conducted by Tadvi N A et al 4 Majority of the subjects which is included in the study were from the age group of 40-49 years + 12.9 which is related to the mean age of 43.9 + 17.8 in a study conducted by Amoako A Y et al 5 The most commonly prescribed class of drug in our study w-as found to be Anti-Hypertensives(89.9%).…”

A Prospective Observational Study on Medication Use Pattern in Patients With Risk Factors of Chronic Kidney Disease

“…Among the cardiovascular drugs, calcium channel blockers (CCBs) were most commonly prescribed (18.91%) in our study. Similar results were reported by Shastry et al [5], Bailie et al [17], Dasari et al [18], and Tadvi and Hussain [19] where CCBs were most commonly prescribed constituting 78.05%, 27.6%, 60.5%, and 52%, respectively . Where as studies conducted by Chakraborty et al [9], Ahlawat et al [12], and Bajait et al [13] constituting 9.29%, 54%, 9.50% respectively followed by CCBs.…”

Test

“…There are limited studies on CKD medication pro ile in Hyderabad, India. Medical audits help to achieve rational use of drugs [2]. Thus this present study aim was to assess prescription pattern in patients with CKD.…”

“…Thus providing medical care to these patients has become a complex job due to their wide spreadco-morbidities and risk factors. Treatment of complications and to prevent or minimize morbidity is the main goal of CKD therapy [1,2].…”