Analysis of platinum-based anticancer injections cisplatin and carboplatin in body fluids blood serum and urine of carcinogenic patients by photometry, fluorometry, liquid chromatography using Schiff-base 2-oxo-propanoic acid- N- phenylhydrazonecarbothioamide as derivatizing reagent
Faiz Muhammad Khokhar,
Taj Muhammad Jahangir,
Muhammad Yar Khuhawar
et al.
Abstract:Photometric, fluorometric and liquid chromatographic methods were proposed to analyze platinum(II) from cis-platin and carbo-platin injections after derivatization with reagent 2-oxo-propanoic acid N-phenylhydrazonecarbothioamide. The reagent reacted with metals Au(III), Ag(I), Mn(II), Pt(II), Mo(VI), V(V/IV) to develop their characteristic colors in the pH range 3–12 and were extracted in organic solvent trichloromethane. The photoluminescent behaviour of ligand and its metal complexes was investigated to cor… Show more
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