The present article suggests a thermodynamic analysis of flat-plate collector-based single-effect ammonia-water vapor absorption refrigeration system. The investigation involves the development of numerical and computational model based on physical and chemical exergies for the analysis of single-effect absorption systems. The investigation revealed that various operating parameters influence COP, exergy loss in different components as well as exergy efficiency. The COP cooling , COP heating and exergy efficiency show a decreasing trend with an increase in the generator temperature (60-100°C) and lie in the range of 0.398-0.435, 1.39-1.43 and 0.1421-0.2975, respectively. The COP cooling and COP heating show an increasing trend with an increase in the evaporator temperature, whereas exergy efficiency shows a decreasing trend with an increase in the evaporator temperature. However, The COP cooling , COP heating and exergy efficiency show a decreasing trend with an increase in absorber and condenser temperature. The variation in physical ðW PH loss Þ and chemical exergy losses ðW CH loss Þ with ambient temperature has also been discussed in the analysis. It is noticed that the highest percentage of non-dimensional physical and chemical exergy losses are found to be in the generator. The second worst component from the non-dimensional physical and chemical irreversibility viewpoints is the absorber, followed by solution heat exchanger, evaporator and condenser.